Anti-ALDH1A2 antibody (ab96060)
Key features and details
- Rabbit polyclonal to ALDH1A2
- Suitable for: WB, IHC-P
- Reacts with: Mouse, Human
- Isotype: IgG
Overview
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Product name
Anti-ALDH1A2 antibody
See all ALDH1A2 primary antibodies -
Description
Rabbit polyclonal to ALDH1A2 -
Host species
Rabbit -
Tested applications
Suitable for: WB, IHC-Pmore details -
Species reactivity
Reacts with: Mouse, Human
Predicted to work with: Rat
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Immunogen
Recombinant fragment, corresponding to a region within amino acids 240-457 of Human ALDH1A2.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
Storage buffer
pH: 7.00
Preservative: 0.025% Proclin 300
Constituents: 78% PBS, 1% BSA, 20% Glycerol (glycerin, glycerine) -
Concentration information loading... -
Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab96060 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| WB | (5) |
1/500 - 1/3000. Predicted molecular weight: 57 kDa.
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| IHC-P | (1) |
1/100 - 1/1000.
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| Notes |
|---|
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WB
1/500 - 1/3000. Predicted molecular weight: 57 kDa. |
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IHC-P
1/100 - 1/1000. |
Target
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Function
Recognizes as substrates free retinal and cellular retinol-binding protein-bound retinal. Does metabolize octanal and decanal but does not metabolize citral, benzaldehyde, acetaldehyde and propanal efficiently. -
Pathway
Cofactor metabolism; retinol metabolism. -
Sequence similarities
Belongs to the aldehyde dehydrogenase family. -
Cellular localization
Cytoplasm. - Information by UniProt
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Database links
- Entrez Gene: 8854 Human
- Entrez Gene: 19378 Mouse
- Entrez Gene: 116676 Rat
- Omim: 603687 Human
- SwissProt: O94788 Human
- SwissProt: Q62148 Mouse
- SwissProt: Q63639 Rat
- Unigene: 643455 Human
see all -
Alternative names
- AL1A2_HUMAN antibody
- Aldehyde dehydrogenase family 1 member A2 antibody
- ALDH1A2 aldehyde dehydrogenase 1 family, member A2 antibody
see all
Images
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Western blot - Anti-ALDH1A2 antibody (ab96060)Anti-ALDH1A2 antibody (ab96060) at 1/1000 dilution + IMR32 whole cell lysate at 30 µg
Predicted band size: 57 kDa
10% SDS PAGE -
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ALDH1A2 antibody (ab96060)Immunohistochemical analysis of PFA fixed, paraffin-embedded mouse testis tissue labeling ALDH1A2 with ab96060 at 1/500 dilution.
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (5)
ab96060 has been referenced in 5 publications.
- Wojahn I et al. TBX2-positive cells represent a multi-potent mesenchymal progenitor pool in the developing lung. Respir Res 20:292 (2019). PubMed: 31870435
- Magella B et al. Reduced Abd-B Hox function during kidney development results in lineage infidelity. Dev Biol 438:84-93 (2018). IHC-P, IF . PubMed: 29596840
- Hägglund AC et al. A novel mouse model of anterior segment dysgenesis (ASD): conditional deletion of Tsc1 disrupts ciliary body and iris development. Dis Model Mech 10:245-257 (2017). PubMed: 28250050
- House CD et al. NF?B Promotes Ovarian Tumorigenesis via Classical Pathways That Support Proliferative Cancer Cells and Alternative Pathways That Support ALDH+ Cancer Stem-like Cells. Cancer Res 77:6927-6940 (2017). PubMed: 29074539
- Penny HL et al. Restoring Retinoic Acid Attenuates Intestinal Inflammation and Tumorigenesis in APCMin/+ Mice. Cancer Immunol Res 4:917-926 (2016). PubMed: 27638841