Recognizes as substrates free retinal and cellular retinol-binding protein-bound retinal. Does metabolize octanal and decanal but does not metabolize citral, benzaldehyde, acetaldehyde and propanal efficiently.
Yasgar A et al. A High-Content Assay Enables the Automated Screening and Identification of Small Molecules with Specific ALDH1A1-Inhibitory Activity. PLoS One12:e0170937 (2017).
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Lee H et al. Fusion protein of retinol-binding protein and albumin domain III reduces liver fibrosis. EMBO Mol Med7:819-30 (2015).
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