Overview

  • Product name
    Anti-ALDH1L1 antibody [EPR12744(B)]
    See all ALDH1L1 primary antibodies
  • Description
    Rabbit monoclonal [EPR12744(B)] to ALDH1L1
  • Host species
    Rabbit
  • Tested applications
    Suitable for: IHC-P, WB, IPmore details
    Unsuitable for: ICC/IF
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human ALDH1L1 aa 850 to the C-terminus (Cysteine residue). The exact sequence is proprietary.
    Database link: O75891

  • Positive control
    • Human fetal liver and kidney lysates; Human kidney and liver tissues.
  • General notes

     

     

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

    This product is a recombinant rabbit monoclonal antibody.

Properties

Applications

Our Abpromise guarantee covers the use of ab175198 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
WB 1/1000 - 1/5000. Predicted molecular weight: 99 kDa.
IP 1/10 - 1/100.
  • Application notes
    Is unsuitable for ICC/IF.
  • Target

    • Tissue specificity
      Highly expressed in liver, pancreas and kidney.
    • Sequence similarities
      In the N-terminal section; belongs to the GART family.
      In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily.
      Contains 1 acyl carrier domain.
    • Cellular localization
      Cytoplasm.
    • Information by UniProt
    • Database links
    • Alternative names
      • 10 formyltetrahydrofolate dehydrogenase antibody
      • 10 FTHFDH antibody
      • 10-formyltetrahydrofolate dehydrogenase antibody
      • 10-FTHFDH antibody
      • AL1L1_HUMAN antibody
      • Aldehyde dehydrogenase 1 family member L1 antibody
      • Aldehyde dehydrogenase family 1 member L1 antibody
      • aldh1l1 antibody
      • Cytosolic 10-formyltetrahydrofolate dehydrogenase antibody
      • DKFZp781N0997 antibody
      • EC 1.5.1.6 antibody
      • FDH antibody
      • formyltetrahydrofolate dehydrogenase antibody
      • FTHFD antibody
      • OTTHUMP00000155221 antibody
      • OTTHUMP00000214696 antibody
      • OTTHUMP00000214700 antibody
      • OTTHUMP00000222724 antibody
      see all

    Images

    • All lanes : Anti-ALDH1L1 antibody [EPR12744(B)] (ab175198) at 1/1000 dilution

      Lane 1 : Human fetal liver lysates
      Lane 2 : Human fetal kidney lysates

      Lysates/proteins at 10 µg per lane.

      Predicted band size: 99 kDa

    • Immunohistochemical analysis of paraffin-embedded Human kidney tissue labeling ALDH1L1 with ab175198 at a 1/50 dilution.

    • Immunohistochemical analysis of paraffin-embedded Human liver tissue labeling ALDH1L1 with ab175198 at a 1/50 dilution.

    • Western blot analysis on immunoprecipitation pellet from Human fetal liver lysate labeling ALDH1L1 using ab175198 at a 1/10 dilution.

    References

    This product has been referenced in:
    • Kang JH  et al. Aldehyde dehydrogenase inhibition combined with phenformin treatment reversed NSCLC through ATP depletion. Oncotarget 7:49397-49410 (2016). Read more (PubMed: 27384481) »
    See 1 Publication for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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