ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde. They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. This protein preferentially oxidizes aromatic aldehyde substrates. It may play a role in the oxidation of toxic aldehydes.
High levels in stomach, esophagus and lung; low level in the liver and kidney.
Immunocytochemistry/Immunofluorescence analysis of U2OS cells using ab186726. Blue DAPI for nuclear staining.
Western blot - Anti-ALDH3A1 antibody (ab186726)
All lanes : Anti-ALDH3A1 antibody (ab186726) at 1/500 dilution
Lane 1 : Extract of A549 cell line Lane 2 : Extract of H460 cell line Lane 3 : Extract of HT29 cell line Lane 4 : Extract of Hela cell line Lane 5 : Extract of mouse lung cell line Lane 6 : Extract of mouse testis cell line Lane 7 : Extract of mouse stomach cell line Lane 8 : Extract of mouse brain cell line