Overview

  • Product name

    Anti-ALDH3A1 antibody [EPR7406]
    See all ALDH3A1 primary antibodies
  • Description

    Rabbit monoclonal [EPR7406] to ALDH3A1
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
    Unsuitable for: Flow Cyt,ICC/IF,IHC-P or IP
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide corresponding to residues on the C-terminus of Human ALDH3A1.

  • Positive control

    • A549, Mouse eyeball and Rat eyeball lysates.
  • General notes

     

     

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.

    This product is a recombinant rabbit monoclonal antibody.

Properties

Applications

Our Abpromise guarantee covers the use of ab129022 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Detects a band of approximately 50 kDa (predicted molecular weight: 50 kDa).
  • Application notes
    Is unsuitable for Flow Cyt,ICC/IF,IHC-P or IP.
  • Target

    • Function

      ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde. They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. This protein preferentially oxidizes aromatic aldehyde substrates. It may play a role in the oxidation of toxic aldehydes.
    • Tissue specificity

      High levels in stomach, esophagus and lung; low level in the liver and kidney.
    • Sequence similarities

      Belongs to the aldehyde dehydrogenase family.
    • Cellular localization

      Cytoplasm.
    • Information by UniProt
    • Database links

    • Alternative names

      • Acetaldehyde dehydrogenase 3 antibody
      • AHD 4 antibody
      • AHD C antibody
      • AHD4 antibody
      • AHDC antibody
      • AL3A1_HUMAN antibody
      • Aldehyde dehydrogenase 3 antibody
      • Aldehyde dehydrogenase 3 family member A1 antibody
      • Aldehyde dehydrogenase 3A1 antibody
      • Aldehyde dehydrogenase antibody
      • Aldehyde dehydrogenase class 3 antibody
      • Aldehyde dehydrogenase dimeric NADP preferring antibody
      • Aldehyde dehydrogenase family 3 member A1 antibody
      • Aldehyde dehydrogenase family 3 subfamily A1 antibody
      • Aldehyde dehydrogenase family 3, subfamily A, member 1 antibody
      • Aldehyde dehydrogenase isozyme 3 antibody
      • Aldehyde dehydrogenase type III antibody
      • ALDH 3 antibody
      • ALDH 3A1 antibody
      • ALDH III antibody
      • ALDH, stomach type antibody
      • ALDH3 A1 antibody
      • ALDH3 antibody
      • ALDH3A 1 antibody
      • Aldh3a1 antibody
      • ALDHIII antibody
      • dimeric NADP-preferring antibody
      • MGC10406 antibody
      • Stomach aldehyde dehydrogenase antibody
      • Tumor associated aldehyde dehydrogenase tumor ALDH antibody
      see all

    Images

    • All lanes : Anti-ALDH3A1 antibody [EPR7406] (ab129022) at 1/1000 dilution

      Lane 1 : A549 cell lysates
      Lane 2 : Mouse eyeball lysates
      Lane 3 : Rat eyeball lysates

      Lysates/proteins at 10 µg per lane.

      Secondary
      All lanes : HRP-conjugated goat anti-abbit at 1/2000 dilution

      Predicted band size: 50 kDa
      Observed band size: 50 kDa

    • Equilibrium disassociation constant (KD)
      Learn more about KD

      Click here to learn more about KD

    References

    This product has been referenced in:

    • Yasgar A  et al. A High-Content Assay Enables the Automated Screening and Identification of Small Molecules with Specific ALDH1A1-Inhibitory Activity. PLoS One 12:e0170937 (2017). Read more (PubMed: 28129349) »
    • Duong HQ  et al. Silencing of NRF2 Reduces the Expression of ALDH1A1 and ALDH3A1 and Sensitizes to 5-FU in Pancreatic Cancer Cells. Antioxidants (Basel) 6:N/A (2017). Read more (PubMed: 28671577) »
    See all 3 Publications for this product

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab129022.
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    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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