• Product name

    Anti-ALDH5A1/SSADH antibody
    See all ALDH5A1/SSADH primary antibodies
  • Description

    Rabbit polyclonal to ALDH5A1/SSADH
  • Host species

  • Tested applications

    Suitable for: WB, IHC-P, ICC/IFmore details
  • Species reactivity

    Reacts with: Mouse, Human
    Predicted to work with: Cow
  • Immunogen

    Recombinant fragment corresponding to Human ALDH5A1/SSADH aa 85-324.
    Database link: P51649

  • Positive control

    • 293T, A431, H1299, HeLa, HepG2, MOLT4, Raji, Mouse brain whole cell lysate; A431 cells; A549 xenograft
  • General notes

    Keep as a concentrated solution.

     This product was previously labelled as ALDH5A1




Our Abpromise guarantee covers the use of ab155493 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Predicted molecular weight: 57 kDa.
IHC-P 1/100 - 1/1000. Suggested antigen retrieval using heat mediated 10mM Citrate buffer (pH6.0) or Tris-EDTA buffer (pH8.0).
ICC/IF 1/100 - 1/1000.


  • Function

    Catalyzes one step in the degradation of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA).
  • Tissue specificity

    Brain, pancreas, heart, liver, skeletal muscle and kidney. Lower in placenta.
  • Pathway

    Amino-acid degradation; 4-aminobutanoate degradation.
  • Involvement in disease

    Defects in ALDH5A1 are the cause of succinate semialdehyde dehydrogenase deficiency (SSADH deficiency) [MIM:271980]. SSADH deficiency is a rare inborn error in the metabolism of 4-aminobutyric acid (GABA) which leads to accumulation of 4-hydroxybutyric acid in physiologic fluids of patients. The disease is characterized by severe ataxia and by mildly retarded psychomotor development.
  • Sequence similarities

    Belongs to the aldehyde dehydrogenase family.
  • Cellular localization

  • Information by UniProt
  • Database links

  • Alternative names

    • Aldedehyde dehydrogenase 5 family antibody
    • Aldehyde dehydrogenase 5 family member A1 antibody
    • Aldehyde dehydrogenase 5A1 antibody
    • Aldehyde dehydrogenase family 5 member A1 antibody
    • ALDH5A 1 antibody
    • Aldh5a1 antibody
    • mitochondrial antibody
    • Mitochondrial succinate semialdehyde dehydrogenase antibody
    • NAD(+) dependent succinic semialdehyde dehydrogenase antibody
    • NAD(+)-dependent succinic semialdehyde dehydrogenase antibody
    • SSADH antibody
    • SSDH antibody
    • SSDH_HUMAN antibody
    • Succinate semialdehyde dehydrogenase antibody
    • Succinate-semialdehyde dehydrogenase antibody
    see all


  • Anti-ALDH5A1/SSADH antibody (ab155493) at 1/1000 dilution + A431 whole cell lysate at 30 µg

    Predicted band size: 57 kDa

    7.5% SDS PAGE
  • Paraffin-embedded mouse liver tissue labeling ALDH5A1/SSADH using ab155493 at 1/500 dilution in immunohistochemical analysis.

    Antigen Retrieval: Citrate buffer, pH 6.0, 15 minutes.

  • Anti-ALDH5A1/SSADH antibody (ab155493) at 1/5000 dilution + Mouse brain whole cell lysate at 20 µg

    Predicted band size: 57 kDa

    7.5% SDS PAGE
  • Immunofluorescent analysis of methanol-fixed A431 cells labeling ALDH5A1/SSADH with ab155493 at 1/500 dilution. Lower panel co-stained with Hoescht 33342.

  • Immunohistochemical analysis of paraffin-embedded A549 xenograft labeling ALDH5A1/SSADH with ab155493 at 1/500 dilution.


ab155493 has not yet been referenced specifically in any publications.

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