Overview

  • Product name

  • Description

    Rabbit polyclonal to Aldolase
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
    Unsuitable for: IP
  • Species reactivity

    Reacts with: Mouse, Human
    Predicted to work with: Rat, Rabbit, Chimpanzee, Orangutan
  • Immunogen

    Synthetic peptide within Human Aldolase aa 50-100. The exact sequence is proprietary. NP_000025.1
    Database link: P04075

  • Positive control

    • WB: HeLa, HEK-293T, Jurkat, TCMK-1 and NIH/3T3 whole cell lysates.

Properties

Applications

Our Abpromise guarantee covers the use of ab245468 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/2000 - 1/10000. Predicted molecular weight: 39 kDa.
  • Application notes
    Is unsuitable for IP.
  • Target

    • Function

      Plays a key role in glycolysis and gluconeogenesis. In addition, may also function as scaffolding protein.
    • Pathway

      Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 4/4.
    • Involvement in disease

      Defects in ALDOA are the cause of glycogen storage disease type 12 (GSD12) [MIM:611881]; also known as red cell aldolase deficiency. A metabolic disorder associated with increased hepatic glycogen and hemolytic anemia. It may lead to myopathy with exercise intolerance and rhabdomyolysis.
    • Sequence similarities

      Belongs to the class I fructose-bisphosphate aldolase family.
    • Information by UniProt
    • Database links

    • Alternative names

      • ALDA antibody
      • Aldo1 antibody
      • ALDOA antibody
      • ALDOA_HUMAN antibody
      • Aldolase 1 antibody
      • Aldolase A antibody
      • Aldolase A fructose bisphosphatase antibody
      • Aldolase A fructose bisphosphate antibody
      • Aldolase, fructose-bisphosphate A antibody
      • Epididymis secretory sperm binding protein Li 87p antibody
      • FRUCTOALDOLASE A antibody
      • Fructose 1 6 bisphosphate triosephosphate lyase antibody
      • Fructose bisphosphate aldolase A antibody
      • Fructose bisphosphate aldolase antibody
      • FRUCTOSE-1,6-BISPHOSPHATE ALDOLASE A antibody
      • Fructose-bisphosphate aldolase A antibody
      • Fructose-bisphosphate aldolase A Muscle-type antibody
      • GSD12 antibody
      • HEL S 87p antibody
      • Lung cancer antigen NY LU 1 antibody
      • Lung cancer antigen NY-LU-1 antibody
      • MGC10942 antibody
      • MGC17716 antibody
      • MGC17767 antibody
      • Muscle type aldolase antibody
      • Muscle-type aldolase antibody
      • RNALDOG5 antibody
      see all

    Images

    • All lanes : Anti-Aldolase antibody (ab245468) at 0.1 µg/ml

      Lane 1 : HeLa (human epithelial cell line from cervix adenocarcinoma) whole cell lysate
      Lane 2 : HEK-293T (human epithelial cell line from embryonic kidney transformed with large T antigen) whole cell lysate
      Lane 3 : Jurkat (human T cell leukemia cell line from peripheral blood) whole cell lysate
      Lane 4 : TCMK-1 (mouse kidney epithelial cell line) whole cell lysate
      Lane 5 : NIH/3T3 (mouse embryo fibroblast cell line) whole cell lysate

      Lysates/proteins at 50 µg per lane.

      Developed using the ECL technique.

      Predicted band size: 39 kDa


      Exposure time: 30 seconds

    References

    ab245468 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab245468.
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