Alexa Fluor® 488 Anti-CD105 antibody [MEM226], prediluted (ab187575)

Submit a review Submit a question
Flow Cytometry - Alexa Fluor® 488 Anti-CD105 antibody [MEM226], prediluted (ab187575)

    Key features and details

    • Alexa Fluor® 488 Mouse monoclonal [MEM226] to CD105, prediluted
    • Suitable for: Flow Cyt
    • Reacts with: Human
    • Conjugation: Alexa Fluor® 488. Ex: 495nm, Em: 519nm
    • Isotype: IgG2a

    Overview

    • Product name

      Alexa Fluor® 488 Anti-CD105 antibody [MEM226], prediluted
      See all CD105 primary antibodies

    • Description

      Alexa Fluor® 488 Mouse monoclonal [MEM226] to CD105, prediluted

    • Host species

      Mouse

    • Conjugation

      Alexa Fluor® 488. Ex: 495nm, Em: 519nm

    • Tested applications

      Suitable for: Flow Cytmore details

    • Species reactivity

      Reacts with: Human

    • Immunogen

      Recombinant full length protein corresponding to Human CD105. Human CD105 cDNA was expressed in recombinant Vaccinia virus.
      Database link: P17813

    • General notes

      Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.

      Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.

      We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.

      In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.

      We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.

      Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.

      Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.

    Properties

    Applications

    Our Abpromise guarantee covers the use of ab187575 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Abreviews Notes
    Flow Cyt Use 4µl for 106 cells.

    Use 4 µl for 100 µl of Human whole blood cells in suspension.

     

     

     

     

    ab171464 - Mouse monoclonal IgG2a, is suitable for use as an isotype control with this antibody.

     

    Target

    • Function

      Major glycoprotein of vascular endothelium. May play a critical role in the binding of endothelial cells to integrins and/or other RGD receptors.

    • Tissue specificity

      Endoglin is restricted to endothelial cells in all tissues except bone marrow.

    • Involvement in disease

      Defects in ENG are the cause of hereditary hemorrhagic telangiectasia type 1 (HHT1) [MIM:187300, 108010]; also known as Osler-Rendu-Weber syndrome 1 (ORW1). HHT1 is an autosomal dominant multisystemic vascular dysplasia, characterized by recurrent epistaxis, muco-cutaneous telangiectases, gastro-intestinal hemorrhage, and pulmonary (PAVM), cerebral (CAVM) and hepatic arteriovenous malformations; all secondary manifestations of the underlying vascular dysplasia. Although the first symptom of HHT1 in children is generally nose bleed, there is an important clinical heterogeneity.

    • Cellular localization

      Membrane.
    • Information by UniProt

    • Database links

      • Alternative names

        • AI528660 antibody
        • AI662476 antibody
        • CD 105 antibody
        • CD105 antibody
        • CD105 antigen antibody
        • EGLN_HUMAN antibody
        • END antibody
        • Endoglin antibody
        • Eng antibody
        • FLJ41744 antibody
        • HHT1 antibody
        • ORW antibody
        • ORW1 antibody
        • Osler Rendu Weber syndrome 1 antibody
        • RP11 228B15.2 antibody
        • S endoglin antibody
        • S-endoglin antibody
        • SN6 antibody
        see all

      Images

      • Flow Cytometry - Alexa Fluor® 488 Anti-CD105 antibody [MEM226], prediluted (ab187575)
        Flow Cytometry - Alexa Fluor® 488 Anti-CD105 antibody [MEM226], prediluted (ab187575)
        Surface staining of HUVEC (human umbilical vein endothelial cells) with ab187575 at 1/25 dilution

      References (0)

      Publishing research using ab187575? Please let us know so that we can cite the reference in this datasheet.

      ab187575 has not yet been referenced specifically in any publications.

      Customer reviews and Q&As

      Show All Reviews Q&A
      Submit a review Submit a question

      There are currently no Customer reviews or Questions for ab187575.
      Please use the links above to contact us or submit feedback about this product.

      Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
      For licensing inquiries, please contact partnerships@abcam.com