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    alexa-fluor-488-lamp1-antibody-h4a3-ab187591.pdf

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Alexa Fluor® 488 Anti-LAMP1 antibody [H4A3] (ab187591)

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Flow Cytometry - Alexa Fluor® 488 Anti-LAMP1 antibody [H4A3] (ab187591)

    Key features and details

    • Alexa Fluor® 488 Mouse monoclonal [H4A3] to LAMP1
    • Suitable for: Flow Cyt
    • Reacts with: Mouse, Human, Non human primates
    • Conjugation: Alexa Fluor® 488. Ex: 495nm, Em: 519nm
    • Isotype: IgG1

    You may also be interested in

    Protein
    Recombinant Human LAMP1 protein (ab151863)
    Conjugation
    Product image
    Alexa Fluor® 488 Conjugation Kit (Fast) - Lightning-Link® (ab236553)

    View more associated products

    Overview

    • Product name

      Alexa Fluor® 488 Anti-LAMP1 antibody [H4A3]
      See all LAMP1 primary antibodies
    • Description

      Alexa Fluor® 488 Mouse monoclonal [H4A3] to LAMP1
    • Host species

      Mouse
    • Conjugation

      Alexa Fluor® 488. Ex: 495nm, Em: 519nm
    • Tested applications

      Suitable for: Flow Cytmore details
    • Species reactivity

      Reacts with: Mouse, Human, Non human primates
    • Immunogen

      Tissue, cells or virus corresponding to Human LAMP1. Human PBMC (Human Peripheral Blood Mononuclear Cells).

    • Positive control

      • Human blood cells.
    • General notes

      Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.

      Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.

      We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.

      In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.

      We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.

      Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.

      Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.

    Properties

    • Form

      Liquid
    • Storage instructions

      Shipped at 4°C. Store at +4°C. Store In the Dark.
    • Storage buffer

      pH: 7.4
      Preservative: 0.097% Sodium azide
      Constituents: 0.2% BSA, 99% PBS
    • Concentration information loading...
    • Purity

      Size exclusion
    • Clonality

      Monoclonal
    • Clone number

      H4A3
    • Isotype

      IgG1
    • Research areas

      • Neuroscience
      • Cell Type Marker
      • Neuron marker
      • Soma marker
      • Neuroscience
      • Cell Type Marker
      • Neuron marker
      • Growth Cone
      • Tags & Cell Markers
      • Subcellular Markers
      • Organelles
      • Lysosome
      • Signal Transduction
      • Protein Trafficking
      • Organelle Proteins
      • Neuroscience
      • Neurology process
      • Neurogenesis
      • Stem Cells
      • Hematopoietic Progenitors
      • Lymphoid
      • B Lymphocytic Lineage
      • Stem Cells
      • Hematopoietic Progenitors
      • Lymphoid
      • T Lymphocytic Lineage
      • Stem Cells
      • Hematopoietic Progenitors
      • Myeloid
      • Monocytic Lineage
      • Cancer
      • Signal transduction
      • Autophagy
      • Metabolism
      • Pathways and Processes
      • Metabolism processes
      • Autophagy and mitophagy
      • Cancer
      • Cell Death
      • Autophagy
      • Signal Transduction

    Associated products

    • Alternative Versions

      • Anti-LAMP1 antibody [H4A3] (ab25630)
    • Isotype control

      • AlexaFluor ® 488 Mouse IgG1 [MOPC-21] - Isotype Control (ab234075)
    • Recombinant Protein

      • Recombinant Human LAMP1 protein (ab151863)

    Applications

    Our Abpromise guarantee covers the use of ab187591 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Abreviews Notes
    Flow Cyt Use 4µl for 106 cells.

    or 100 μl of whole blood

     

     

     

     

    ab171463 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.

     

    Target

    • Function

      Presents carbohydrate ligands to selectins. Also implicated in tumor cell metastasis.
    • Sequence similarities

      Belongs to the LAMP family.
    • Post-translational
      modifications

      O- and N-glycosylated; some of the 18 N-linked glycans are polylactosaminoglycans.
    • Cellular localization

      Cell membrane. Endosome membrane. Lysosome membrane. This protein shuttles between lysosomes, endosomes, and the plasma membrane.
    • Target information above from: UniProt accession P11279 The UniProt Consortium
      The Universal Protein Resource (UniProt) in 2010
      Nucleic Acids Res. 38:D142-D148 (2010) .

      Information by UniProt
    • Database links

      • Entrez Gene: 3916 Human
      • Entrez Gene: 16783 Mouse
      • Omim: 153330 Human
      • SwissProt: P11279 Human
      • SwissProt: P11438 Mouse
      • Unigene: 494419 Human
      • Unigene: 16716 Mouse
      • Unigene: 475822 Mouse
      • Alternative names

        • CD107 antigen like family member A antibody
        • CD107 antigen-like family member A antibody
        • CD107a antibody
        • CD107a antigen antibody
        • LAMP 1 antibody
        • LAMP-1 antibody
        • LAMP1 antibody
        • LAMP1_HUMAN antibody
        • LAMPA antibody
        • LGP120 antibody
        • lgpA antibody
        • Lysosomal membrane glycoprotein 120KD antibody
        • Lysosomal Associated Membrane Protein 1 antibody
        • Lysosome associated membrane glycoprotein 1 antibody
        • Lysosome-associated membrane glycoprotein 1 antibody
        • Lysosome-associated membrane protein 1 antibody
        • OTTHUMP00000040663 antibody
        see all

      Images

      • Flow Cytometry - Alexa Fluor® 488 Anti-LAMP1 antibody [H4A3] (ab187591)
        Flow Cytometry - Alexa Fluor® 488 Anti-LAMP1 antibody [H4A3] (ab187591)

        Intracellular staining of human peripheral blood cells with ab187591 4μl reagent /106 cells.

      Protocols

      • Flow cytometry protocols

      Click here to view the general protocols

      Datasheets and documents

      • Datasheet
    • References (1)

      Publishing research using ab187591? Please let us know so that we can cite the reference in this datasheet.

      ab187591 has been referenced in 1 publication.

      • Park H  et al. Tumor Inhibitory Effect of IRCR201, a Novel Cross-Reactive c-Met Antibody Targeting the PSI Domain. Int J Mol Sci 18:N/A (2017). PubMed: 28902178

      Customer reviews and Q&As

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      Please use the links above to contact us or submit feedback about this product.

      Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
      For licensing inquiries, please contact partnerships@abcam.com

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