Alexa Fluor® 647 Anti-CD21 antibody [LT21] (ab187583)
![Flow Cytometry - Alexa Fluor® 647 Anti-CD21 antibody [LT21] (ab187583)](https://www.abcam.com/ps/products/187/ab187583/Images/ab187583-299898-anti-cd21-antibody-lt21-alexa-fluor-647-flow-cytometry.jpg "Flow Cytometry - Alexa Fluor® 647 Anti-CD21 antibody [LT21] (ab187583)")
Key features and details
- Alexa Fluor® 647 Mouse monoclonal [LT21] to CD21
- Suitable for: Flow Cyt
- Reacts with: Cow, Dog, Human, Pig
- Conjugation: Alexa Fluor® 647. Ex: 652nm, Em: 668nm
- Isotype: IgG1
Overview
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Product name
Alexa Fluor® 647 Anti-CD21 antibody [LT21]
See all CD21 primary antibodies -
Description
Alexa Fluor® 647 Mouse monoclonal [LT21] to CD21 -
Host species
Mouse -
Conjugation
Alexa Fluor® 647. Ex: 652nm, Em: 668nm -
Tested applications
Suitable for: Flow Cytmore details -
Species reactivity
Reacts with: Cow, Dog, Human, Pig -
Immunogen
Tissue, cells or virus corresponding to Human CD21. IM9 Human B-lymphoblastoid cell line.
Database link: P20023 -
General notes
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C. Store In the Dark. -
Storage buffer
pH: 7.4
Preservative: 0.097% Sodium azide
Constituents: 99% PBS, 0.2% BSA
High-grade protease free Bovine Serum Albumin
(BSA) is used as a stabilizing agent. -
Concentration information loading... -
Purity
Size exclusion -
Purification notes
The purified antibody is conjugated with Alexa Fluor® 647 under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. -
Clonality
Monoclonal -
Clone number
LT21 -
Isotype
IgG1 -
Research areas
Associated products
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Alternative Versions
Applications
Our Abpromise guarantee covers the use of ab187583 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| Flow Cyt | Use 4µl for 106 cells. ab176103 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.
|
Target
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Function
Receptor for complement C3Dd, for the Epstein-Barr virus on human B-cells and T-cells and for HNRPU. Participates in B lymphocytes activation. -
Tissue specificity
Mature B-lymphocytes, T-lymphocytes, pharyngeal epithelial cells, astrocytes and follicular dendritic cells of the spleen. -
Involvement in disease
Genetic variations in CR2 are associated with susceptibility to systemic lupus erythematosus type 9 (SLEB9) [MIM:610927]. Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with a complex genetic basis. SLE is an inflammatory, and often febrile multisystemic disorder of connective tissue characterized principally by involvement of the skin, joints, kidneys, and serosal membranes. It is thought to represent a failure of the regulatory mechanisms of the autoimmune system. -
Sequence similarities
Belongs to the receptors of complement activation (RCA) family.
Contains 15 Sushi (CCP/SCR) domains. -
Cellular localization
Membrane. - Information by UniProt
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Database links
- Entrez Gene: 1380 Human
- Omim: 120650 Human
- SwissProt: P20023 Human
- Unigene: 445757 Human
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Alternative names
- C3DR antibody
- CD 21 antibody
- CD21 antibody
see all
Images
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Flow Cytometry - Alexa Fluor® 647 Anti-CD21 antibody [LT21] (ab187583)
Surface staining of human peripheral blood leukocytes with ab187583
Datasheets and documents
References (0)
ab187583 has not yet been referenced specifically in any publications.
