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    alexa-fluor-700-cd38-antibody-hit2-ab269302.pdf

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Immunology Adaptive Immunity B Cells CD
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Alexa Fluor® 700 Anti-CD38 antibody [HIT2] (ab269302)

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Abpromise

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Flow Cytometry - Alexa Fluor® 700 Anti-CD38 antibody [HIT2] (ab269302)

    Key features and details

    • Alexa Fluor® 700 Mouse monoclonal [HIT2] to CD38
    • Suitable for: Flow Cyt
    • Reacts with: Human
    • Conjugation: Alexa Fluor® 700
    • Isotype: IgG1

    Overview

    • Product name

      Alexa Fluor® 700 Anti-CD38 antibody [HIT2]
      See all CD38 primary antibodies
    • Description

      Alexa Fluor® 700 Mouse monoclonal [HIT2] to CD38
    • Host species

      Mouse
    • Conjugation

      Alexa Fluor® 700
    • Tested applications

      Suitable for: Flow Cytmore details
    • Species reactivity

      Reacts with: Human
    • Immunogen

      Tissue, cells or virus corresponding to Human CD38. Human thymocytes in foetus
      Database link: P28907

    • Positive control

      • Flow: Human peripheral blood cells.
    • General notes

      Alexa Fluor® is a registered trademark of Molecular Probes, Inc, a Thermo Fisher Scientific Company. The Alexa Fluor® dye included in this product is provided under an intellectual property license from Life Technologies Corporation. As this product contains the Alexa Fluor® dye, the purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). As this product contains the Alexa Fluor® dye the sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: in manufacturing; (ii) to provide a service, information, or data in return for payment (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are sold for use in research. For information on purchasing a license to this product for purposes other than research, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com.

      Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.

      Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.

      We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.

      In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.

      We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.

      Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.

      Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.

    Properties

    • Form

      Liquid
    • Storage instructions

      Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at +4°C. Store In the Dark.
    • Storage buffer

      pH: 7.4
      Preservative: 0.1% Sodium azide
      Constituent: PBS
    • Concentration information loading...
    • Purity

      Size exclusion
    • Clonality

      Monoclonal
    • Clone number

      HIT2
    • Isotype

      IgG1
    • Research areas

      • Immunology
      • Adaptive Immunity
      • B Cells
      • CD
      • Stem Cells
      • Hematopoietic Progenitors
      • Hematopoietic Stem Cells
      • Human Lineage Negative
      • Stem Cells
      • Hematopoietic Progenitors
      • Surface Molecules
      • Stem Cells
      • Hematopoietic Progenitors
      • Lymphoid
      • B Lymphocytic Lineage
      • Stem Cells
      • Hematopoietic Progenitors
      • Lymphoid
      • T Lymphocytic Lineage
      • Stem Cells
      • Hematopoietic Progenitors
      • Lymphoid
      • NK Cell Lineage
      • Stem Cells
      • Hematopoietic Progenitors
      • Myeloid
      • Monocytic Lineage
      • Immunology
      • Adaptive Immunity
      • Regulatory T Cells
      • Cancer
      • Cancer Metabolism
      • Response to hypoxia
      • Metabolism
      • Pathways and Processes
      • Metabolism processes
      • Hypoxia

    Applications

    Our Abpromise guarantee covers the use of ab269302 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Abreviews Notes
    Flow Cyt Use 10µl for 106 cells.

    Target

    • Function

      Synthesizes cyclic ADP-ribose, a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity. Also moonlights as a receptor in cells of the immune system.
    • Tissue specificity

      Expressed at high levels in pancreas, liver, kidney, brain, testis, ovary, placenta, malignant lymphoma and neuroblastoma.
    • Sequence similarities

      Belongs to the ADP-ribosyl cyclase family.
    • Developmental stage

      Preferentially expressed at both early and late stages of the B and T-cell maturation. It is also detected on erythroid and myeloid progenitors in bone marrow, where the level of surface expression was shown to decrease during differentiation of blast-forming unit E to colony-forming unit E.
    • Cellular localization

      Membrane.
    • Target information above from: UniProt accession P28907 The UniProt Consortium
      The Universal Protein Resource (UniProt) in 2010
      Nucleic Acids Res. 38:D142-D148 (2010) .

      Information by UniProt
    • Database links

      • Entrez Gene: 952 Human
      • Omim: 107270 Human
      • SwissProt: P28907 Human
      • Unigene: 479214 Human
      • Form

        There are 2 isoforms produced by alternative splicing.
      • Alternative names

        • Acute lymphoblastic leukemia cells antigen CD38 antibody
        • ADP ribosyl cyclase 1 antibody
        • ADP ribosyl cyclase antibody
        • ADP ribosyl cyclase/cyclic ADP-ribose hydrolase antibody
        • ADP-ribosyl cyclase 1 antibody
        • ADPRC 1 antibody
        • ADPRC1 antibody
        • cADPr hydrolase 1 antibody
        • CD 38 antibody
        • CD38 antibody
        • CD38 antigen (p45) antibody
        • CD38 antigen antibody
        • CD38 molecule antibody
        • Cd38-rs1 antibody
        • CD38_HUMAN antibody
        • CD38H antibody
        • Cyclic ADP ribose hydrolase antibody
        • Cyclic ADP ribose hydrolase 1 antibody
        • Cyclic ADP-ribose hydrolase 1 antibody
        • EC 3.2.2.5 antibody
        • Ecto nicotinamide adenine dinucleotide glycohydrolase antibody
        • I-19 antibody
        • I19 (mouse) antibody
        • Lymphocyte differentiation antigen CD38 antibody
        • NAD(+) nucleosidase antibody
        • NIM-R5 antigen antibody
        • NIMR5 antigen (mouse) antibody
        • OTTHUMP00000158633 antibody
        • OTTHUMP00000217743 antibody
        • p45 antibody
        • T10 antibody
        see all

      Images

      • Flow Cytometry - Alexa Fluor® 700 Anti-CD38 antibody [HIT2] (ab269302)
        Flow Cytometry - Alexa Fluor® 700 Anti-CD38 antibody [HIT2] (ab269302)
        Flow cytometry analysis (surface staining) of human peripheral blood labeling CD38 with ab269302.

      Protocols

      To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

      Click here to view the general protocols

      Datasheets and documents

      • Datasheet
      • SDS
    • References (0)

      Publishing research using ab269302? Please let us know so that we can cite the reference in this datasheet.

      ab269302 has not yet been referenced specifically in any publications.

      Customer reviews and Q&As

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      There are currently no Customer reviews or Questions for ab269302.
      Please use the links above to contact us or submit feedback about this product.

      Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
      For licensing inquiries, please contact partnerships@abcam.com

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