Anti-ALG1 antibody (ab155935)
Key features and details
- Rabbit polyclonal to ALG1
- Suitable for: WB
- Reacts with: Caenorhabditis elegans
- Isotype: IgG
Overview
-
Product name
Anti-ALG1 antibody
See all ALG1 primary antibodies -
Description
Rabbit polyclonal to ALG1 -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Caenorhabditis elegans -
Immunogen
Synthetic peptide corresponding to Caenorhabditis elegans ALG1 aa 76-97.
Sequence:DLEEIPNSPPTQPQTFSDVPQR
-
Positive control
- Wild type Caenorhabditis elegans extract.
-
General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
-
Form
Liquid -
Storage instructions
Shipped at 4°C. Store at -20°C. -
Storage buffer
Preservative: 0.05% Sodium azide
Constituents: 69% PBS, 30% Glycerol (glycerin, glycerine), 0.1% BSA -
Concentration information loading...
-
Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
-
Compatible Secondaries
-
Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab155935 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
WB |
1/5000. Predicted molecular weight: 112 kDa.
|
Notes |
---|
WB
1/5000. Predicted molecular weight: 112 kDa. |
Target
-
Function
Participates in the formation of the lipid-linked precursor oligosaccharide for N-glycosylation. Involved in assembling the dolichol-pyrophosphate-GlcNAc(2)-Man(5) intermediate on the cytoplasmic surface of the ER. -
Pathway
Protein modification; protein glycosylation. -
Involvement in disease
Defects in ALG1 are the cause of congenital disorder of glycosylation type 1K (CDG1K) [MIM:608540]. CDGs are a family of severe inherited diseases caused by a defect in protein N-glycosylation. They are characterized by under-glycosylated serum proteins. These multisystem disorders present with a wide variety of clinical features, such as disorders of the nervous system development, psychomotor retardation, dysmorphic features, hypotonia, coagulation disorders, and immunodeficiency. The broad spectrum of features reflects the critical role of N-glycoproteins during embryonic development, differentiation, and maintenance of cell functions. -
Sequence similarities
Belongs to the glycosyltransferase 1 family. -
Cellular localization
Endoplasmic reticulum membrane. - Information by UniProt
-
Alternative names
- 4-mannosyltransferase antibody
- Alg1 antibody
- ALG1_HUMAN antibody
see all
Images
-
All lanes : Anti-ALG1 antibody (ab155935) at 1/5000 dilution
Lane 1 : Wild type Caenorhabditis elegans extract
Lane 2 : ALG1 negative (-) Caenorhabditis elegans extract
Lysates/proteins at 15 µg per lane.
Secondary
All lanes : Goat anti-rabbit HRP conjugated antibody at 1/15000 dilution
Predicted band size: 112 kDa
4-20% Tris-HCl polyacrylamide gel.
Datasheets and documents
-
SDS download
-
Datasheet download
References (0)
ab155935 has not yet been referenced specifically in any publications.