Key features and details
- Mouse polyclonal to ALK-7
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Product nameAnti-ALK-7 antibody
See all ALK-7 primary antibodies
DescriptionMouse polyclonal to ALK-7
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Human
Full length protein corresponding to Human ALK-7 aa 1-493. NP_660302.1
- WB: ALK-7 transfected HEK-293T cell lysate.
Protein previously known as Activin A Receptor Type IC.
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage bufferpH: 7.20
Concentration information loading...
PurityProtein G purified
Our Abpromise guarantee covers the use of ab67921 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500 - 1/1000. Predicted molecular weight: 55 kDa.|
FunctionSerine/threonine protein kinase which forms a receptor complex on ligand binding. The receptor complex consisting of 2 type II and 2 type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators, SMAD2 and SMAD3. Receptor for activin AB, activin B and NODAL. Plays a role in cell differentiation, growth arrest and apoptosis.
Tissue specificityPresent in pancreas, heart, colon, small intestine, ovary and the hippocampus, medulla oblongata and putamen of the brain. Isoform 1, isoform 2, isoform 3 and isoform 4 are all expressed in the placenta throughout pregnancy.
Sequence similaritiesBelongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
Contains 1 GS domain.
Contains 1 protein kinase domain.
- Information by UniProt
- Activin A receptor, type IC antibody
- Activin receptor like kinase 7 antibody
- Activin receptor type 1C precursor antibody
All lanes : Anti-ALK-7 antibody (ab67921) at 1/500 dilution
Lane 1 : ALK-7 transfected HEK-293T cell lysate
Lane 2 : Non-transfected HEK-293T cell lysate
Lysates/proteins at 25 µg per lane.
All lanes : Goat anti-mouse IgG (H&L)-HRP at 1/2000 dilution
Predicted band size: 55 kDa
Observed band size: 50 kDa why is the actual band size different from the predicted?
ab67921 has not yet been referenced specifically in any publications.