Overview

  • Product name
    all-trans Retinol (Vitamin A)
  • Description
    Retinoic acid receptor ligand
  • Alternative names
    • Vitamin A
  • Biological description
    Retinoic acid receptor ligand. Retinoid, derivative of vitamin A. Regulates gene transcription in cells. Inhibitor of rod channels (IC50 = 0.99 μM).
  • Purity
    > 98%

Properties

References

This product has been referenced in:
  • Blomhoff R & Blomhoff HK Overview of retinoid metabolism and function. J Neurobiol 66:606-30 (2006). Read more (PubMed: 16688755) »
  • Lane MA & Bailey SJ Role of retinoid signalling in the adult brain. Prog Neurobiol 75:275-93 (2005). Read more (PubMed: 15882777) »
  • Dean DM  et al. All-trans-retinal shuts down rod cyclic nucleotide-gated ion channels: a novel role for photoreceptor retinoids in the response to bright light? Proc Natl Acad Sci U S A 99:8372-7 (2002). Read more (PubMed: 12034887) »
  • Repa JJ  et al. All-trans-retinol is a ligand for the retinoic acid receptors. Proc Natl Acad Sci U S A 90:7293-7 (1993). Read more (PubMed: 8394016) »

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"

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