Overview

  • Product name

    Allopurinol, Xanthine oxidase inhibitor
  • Description

    Xanthine oxidase inhibitor
  • Biological description

    Xanthine oxidase inhibitor (IC50 = 0.2 - 50 μM). Anti-hyperuricemic purine analog. Inhibits uric acid production in vivo. Neuroprotective. Active in vivo.
  • Purity

    > 98%
  • CAS Number

    315-30-0
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    1,2-Dihydropyrazolo[3,4-d]pyrimidin-4-one
  • Molecular weight

    136.11
  • Molecular formula

    C5H4N4O
  • PubChem identifier

    2094
  • Storage instructions

    Store at Room Temperature. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in water to 25 mM, in DMSO to 100 mM and in ethanol to 10 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Toxic, refer to SDS for further information.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    C1=C2C(=NC=NC2=O)NN1
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:

  • Mesquita Casagrande AC  et al. In vitro stimulation of oxidative stress by hypoxanthine in blood of rats: prevention by vitamins e plus C and allopurinol. Nucleosides Nucleotides Nucleic Acids 32:42-57 (2013). Read more (PubMed: 23360294) »
  • Ansari MA  et al. Neuroprotective effect of allopurinol and nimesulide against cerebral ischemic reperfusion injury in diabetic rats. Eur Rev Med Pharmacol Sci 17:170-8 (2013). Read more (PubMed: 23377804) »
  • Pacher P  et al. Therapeutic effects of xanthine oxidase inhibitors: renaissance half a century after the discovery of allopurinol. Pharmacol Rev 58:87-114 (2006). Read more (PubMed: 16507884) »

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab142565.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES, NOT FOR USE IN HUMANS"
For licensing inquiries, please contact partnerships@abcam.com

Sign up