Allylthiourea, Metabolic inhibitor (ab145720)

Overview

  • Product name

    Allylthiourea, Metabolic inhibitor
  • Description

    Metabolic inhibitor. Selective inhibitor of ammonia oxidation.
  • Alternative names

    • 1-Allyl-2-thiourea
    • N-Allylthiourea
    • Thiosinamine
  • Biological description

    Metabolic inhibitor. Selective inhibitor of ammonia oxidation. Probably acts through chelating the copper of the ammonia monooxygenase active site.

  • Purity

    > 99%
  • CAS Number

    109-57-9
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    N-2-Propen-1-ylthiourea
  • Molecular weight

    116.18
  • Molecular formula

    C4H8N2S
  • Storage instructions

    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in DMSO to 100 mM and in ethanol to 100 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • Source

    Synthetic

References

This product has been referenced in:

  • Yu Y  et al. Use of allylthiourea to produce soluble methane monooxygenase in the presence of copper. Appl Microbiol Biotechnol 82:333-9 (2009). Read more (PubMed: 19107472) »
  • Ginestet P  et al. Estimation of nitrifying bacterial activities by measuring oxygen uptake in the presence of the metabolic inhibitors allylthiourea and azide Appl Environ Microbiol 64:2266-8 (1998). Read more (PubMed: 9603846) »
  • Bédard C & Knowles R Physiology, biochemistry, and specific inhibitors of CH4, NH4+, and CO oxidation by methanotrophs and nitrifiers. Microbiol Rev 53:68-84 (1989). Read more (PubMed: 2496288) »

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