Anti-ALP antibody (ab229126)
Key features and details
- Rabbit polyclonal to ALP
- Suitable for: WB
- Reacts with: Mouse, Human
- Isotype: IgG
Overview
-
Product name
Anti-ALP antibody
See all ALP primary antibodies -
Description
Rabbit polyclonal to ALP -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Mouse, Human
Predicted to work with: Cow, Rhesus monkey -
Immunogen
Recombinant fragment within Human ALP (internal sequence). The exact sequence is proprietary.
Database link: Q53GG5 -
Positive control
- WB: Mouse muscle lysate; RD whole cell extract.
-
General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
-
Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 20% Glycerol (glycerin, glycerine) -
Concentration information loading...
-
Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
-
Compatible Secondaries
-
Isotype control
-
Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab229126 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
WB |
1/500 - 1/3000. Predicted molecular weight: 39 kDa.
|
Notes |
---|
WB
1/500 - 1/3000. Predicted molecular weight: 39 kDa. |
Target
-
Function
May play a role in the organization of actin filament arrays within muscle cells. -
Tissue specificity
Isoform 1 is highly expressed in differentiated skeletal muscle. Isoform 2 is heart-specific. -
Sequence similarities
Contains 1 LIM zinc-binding domain.
Contains 1 PDZ (DHR) domain. -
Cellular localization
Cytoplasm > myofibril > sarcomere > Z line. Localizes to myofiber Z-lines. - Information by UniProt
-
Database links
- Entrez Gene: 538516 Cow
- Entrez Gene: 27295 Human
- Entrez Gene: 53318 Mouse
- Entrez Gene: 695779 Rhesus monkey
- Omim: 605889 Human
- SwissProt: Q3SYZ8 Cow
- SwissProt: Q53GG5 Human
- SwissProt: O70209 Mouse
see all -
Alternative names
- Actinin associated LIM protein antibody
- Actinin-associated LIM protein antibody
- Alpha actinin 2 associated LIM protein antibody
see all
Images
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
-
SDS download
-
Datasheet download
References (24)
ab229126 has been referenced in 24 publications.
- Xu F et al. H19 Promotes Osteoblastic Transition by Acting as ceRNA of miR-140-5p in Vascular Smooth Muscle Cells. Front Cell Dev Biol 10:774363 (2022). PubMed: 35198556
- Wang N et al. Increased BMSC exosomal miR-140-3p alleviates bone degradation and promotes bone restoration by targeting Plxnb1 in diabetic rats. J Nanobiotechnology 20:97 (2022). PubMed: 35236339
- Cha S et al. Clock-modified mesenchymal stromal cells therapy rescues molecular circadian oscillation and age-related bone loss via miR142-3p/Bmal1/YAP signaling axis. Cell Death Discov 8:111 (2022). PubMed: 35279674
- Zhang K et al. Static magnetic field promotes proliferation, migration, differentiation, and AKT activation of periodontal ligament stem cells. Cells Tissues Organs N/A:N/A (2022). PubMed: 35344952
- He Y et al. Mg(OH)2 nanosheets on Ti with immunomodulatory function for orthopedic applications. Regen Biomater 9:rbac027 (2022). PubMed: 35592137