Overview

  • Product name

    Anti-alpha 1a Adrenergic Receptor/ADRA1A antibody - Cytoplasmic domain
    See all alpha 1a Adrenergic Receptor/ADRA1A primary antibodies
  • Description

    Rabbit polyclonal to alpha 1a Adrenergic Receptor/ADRA1A - Cytoplasmic domain
  • Host species

    Rabbit
  • Specificity

    BLAST analysis of the peptide immunogen showed no homology with other Human proteins.
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat, Sheep, Rabbit, Horse, Guinea pig, Hamster, Cow, Dog, Pig, Monkey
  • Immunogen

    Synthetic peptide corresponding to Human alpha 1a Adrenergic Receptor/ADRA1A. 16 amino acid peptide from 3rd cytoplasmic domain.
    Database link: P35348

  • Positive control

    • Human brain and Human heart (heart failure) tissues.
  • General notes

     This product was previously labelled as alpha 1a Adrenergic Receptor

     

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    Preservative: 0.099% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab219602 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 3 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.

Target

  • Function

    This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins.
  • Tissue specificity

    Expressed in heart, brain, liver and prostate, but not in kidney, lung, adrenal, aorta and pituitary. Within the prostate, expressed in the apex, base, periurethra and lateral lobe. Isoform 4 is the most abundant isoform expressed in the prostate with high levels also detected in liver and heart.
  • Sequence similarities

    Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRA1A sub-subfamily.
  • Post-translational
    modifications

    Carboxyl-terminal Ser or Thr residues may be phosphorylated.
  • Cellular localization

    Cell membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • ADA1A_HUMAN antibody
    • ADRA1A antibody
    • Adra1c antibody
    • ADRA1L1 antibody
    • Adrenergic alpha1A receptor antibody
    • Adrenergic alpha1C receptor antibody
    • Adrenergic receptor alpha 1a antibody
    • Adrenergic receptor alpha 1c antibody
    • Adrenergic, alpha 1A , receptor variant 1 antibody
    • Adrenergic, alpha 1A , receptor variant 11 antibody
    • Adrenergic, alpha 1A , receptor variant 3 antibody
    • Adrenergic, alpha 1A , receptor variant 5 antibody
    • Adrenergic, alpha 1A , receptor variant 8 antibody
    • Adrenoceptor alpha 1A antibody
    • Alpha 1A adrenoreceptor antibody
    • Alpha 1C adrenergic receptor antibody
    • Alpha adrenergic receptor 1c antibody
    • Alpha-1A adrenergic receptor antibody
    • Alpha-1A adrenoceptor antibody
    • Alpha-1A adrenoreceptor antibody
    • Alpha-1C adrenergic receptor antibody
    • Alpha-adrenergic receptor 1c antibody
    • Alpha1A adrenergic receptor antibody
    • ALPHA1AAR antibody
    • G protein coupled receptor antibody
    see all

Images

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human brain tissue labeling alpha 1a Adrenergic Receptor/ADRA1A with ab219602 at 3 µg/ml.

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human heart (heart failure) tissue labeling alpha 1a Adrenergic Receptor/ADRA1A with ab219602 at 3 µg/ml.

References

ab219602 has not yet been referenced specifically in any publications.

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There are currently no Customer reviews or Questions for ab219602.
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