Anti-Alpha 2 Antiplasmin antibody (ab231226)
Key features and details
- Rabbit polyclonal to Alpha 2 Antiplasmin
- Suitable for: WB, IHC-P
- Reacts with: Mouse, Rat
- Isotype: IgG
Overview
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Product name
Anti-Alpha 2 Antiplasmin antibody
See all Alpha 2 Antiplasmin primary antibodies -
Description
Rabbit polyclonal to Alpha 2 Antiplasmin -
Host species
Rabbit -
Tested applications
Suitable for: WB, IHC-Pmore details -
Species reactivity
Reacts with: Mouse, Rat -
Immunogen
Recombinant fragment (His-tag) corresponding to Rat Alpha 2 Antiplasmin aa 300-500. Expressed in E.coli.
Database link: F7FHF3 -
Positive control
- WB: Recombinant rat Alpha 2 Antiplasmin protein; Mouse liver lysate. IHC-P: Rat adrenal gland and liver tissues.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: 44.12% PBS, 55.77% Glycerol (glycerin, glycerine) -
Concentration information loading...
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Purity
Immunogen affinity purified -
Purification notes
Antigen-specific affinity chromatography followed by Protein A affinity chromatography. -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab231226 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
Use a concentration of 0.2 - 2 µg/ml. Predicted molecular weight: 55 kDa.
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IHC-P |
Use a concentration of 5 - 20 µg/ml.
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Notes |
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WB
Use a concentration of 0.2 - 2 µg/ml. Predicted molecular weight: 55 kDa. |
IHC-P
Use a concentration of 5 - 20 µg/ml. |
Target
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Function
Serine protease inhibitor. The major targets of this inhibitor are plasmin and trypsin, but it also inactivates matriptase-3/TMPRSS7 and chymotrypsin. -
Tissue specificity
Expressed by the liver and secreted in plasma. -
Involvement in disease
Defects in SERPINF2 are the cause of alpha-2-plasmin inhibitor deficiency (APLID) [MIM:262850]. APLID is an autosomal recessive disorder resulting in severe hemorrhagic diathesis. -
Sequence similarities
Belongs to the serpin family. -
Cellular localization
Secreted. - Information by UniProt
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Database links
- Entrez Gene: 18816 Mouse
- Entrez Gene: 287527 Rat
- SwissProt: Q61247 Mouse
- Unigene: 279733 Mouse
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Alternative names
- A2AP antibody
- A2AP_HUMAN antibody
- AAP antibody
see all
Images
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Anti-Alpha 2 Antiplasmin antibody (ab231226) at 2 µg/ml + Mouse liver lysate
Predicted band size: 55 kDa -
Anti-Alpha 2 Antiplasmin antibody (ab231226) at 2 µg/ml + Recombinant rat Alpha 2 Antiplasmin protein
Predicted band size: 55 kDa -
Formalin-fixed, paraffin-embedded rat liver tissue stained for Alpha 2 Antiplasmin using ab231226 at 2 µg/mL in immunohistochemical analysis. DAB staining.
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Formalin-fixed, paraffin-embedded rat adrenal tissue stained for Alpha 2 Antiplasmin using ab231226 at 2 µg/mL in immunohistochemical analysis. DAB staining.
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab231226 has not yet been referenced specifically in any publications.