Key features and details
- Rabbit polyclonal to alpha 2a Adrenergic Receptor
- Suitable for: IHC-P
- Reacts with: Rat
- Isotype: IgG
Product nameAnti-alpha 2a Adrenergic Receptor antibody
See all alpha 2a Adrenergic Receptor primary antibodies
DescriptionRabbit polyclonal to alpha 2a Adrenergic Receptor
Tested Applications & Species
Application Species IHC-PRat
- Rat spinal cord dorsal horn, ventral horn motor neurons and retina.
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
Storage bufferPreservative: 0.05% Sodium azide
Concentration information loading...
PurityProtein A purified
Immunizing Peptide (Blocking)
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab92650 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Tested applications are guaranteed to work and covered by our Abpromise guarantee.
Predicted to work for this combination of applications and species but not guaranteed.
Does not work for this combination of applications and species.
Tested on perfusion fixed tissue, using calcium-free Tyrode’s solution, PFA-picric acid fixative, and 10% sucrose in PBS as a cryo-protectant.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
FunctionAlpha-2 adrenergic receptors mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins. The rank order of potency for agonists of this receptor is oxymetazoline > clonidine > epinephrine > norepinephrine > phenylephrine > dopamine > p-synephrine > p-tyramine > serotonin = p-octopamine. For antagonists, the rank order is yohimbine > phentolamine = mianserine > chlorpromazine = spiperone = prazosin > propanolol > alprenolol = pindolol.
Sequence similaritiesBelongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRA2A sub-subfamily.
Cellular localizationCell membrane.
- Information by UniProt
- ADA2A_HUMAN antibody
- ADRA2 antibody
- ADRA2A antibody
ab92650 has not yet been referenced specifically in any publications.