Overview

  • Product name

    Anti-alpha 2C Adrenergic Receptor/ADRA2C antibody
    See all alpha 2C Adrenergic Receptor/ADRA2C primary antibodies
  • Description

    Rabbit polyclonal to alpha 2C Adrenergic Receptor/ADRA2C
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Dog, Monkey, Gorilla
  • Immunogen

    Synthetic peptide corresponding to Human alpha 2C Adrenergic Receptor/ADRA2C (N terminal).

  • Positive control

    • Human artery (smooth muscle) tissue
  • General notes

     This product was previously labelled as alpha 2C Adrenergic Receptor

     

Properties

Applications

Our Abpromise guarantee covers the use of ab140702 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 26 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.

Target

  • Relevance

    The alpha 2C Adrenergic Receptor controls the release of neurotransmitter from central adrenergic neurons and from sympathetic nerves in the heart. This receptor also plays a role in cognitive and behavioral function. Two variants are produced by alternative splicing. Alpha 2C Adrenergic Receptor has been reported extensively in the brain. Blood, corpus cavermosum, kidney, and heart tissues have also been reported to express the protein.
  • Cellular localization

    Cell membrane; Multi-pass membrane protein.
  • Database links

  • Alternative names

    • Adra 2c antibody
    • ADRA2C antibody
    • ADRA2L2 antibody
    • ADRA2RL2 antibody
    • ADRARL2 antibody
    • Adrenergic alpha 2C receptor antibody
    • Adrenoceptor alpha 2C antibody
    • Alpha 2C adrenergic receptor antibody
    • Alpha 2C adrenergic receptor subtype C4 antibody
    • Alpha 2C adrenoceptor antibody
    • Alpha 2C adrenoreceptor antibody
    • Alpha 2CAR antibody
    • Alpha-2-adrenergic receptor, renal type antibody
    • alpha2 AR C4 antibody
    • alpha2 C4 antibody
    • alpha2C antibody
    • ALPHA2CAR antibody
    • alpha2cii-adrenergic receptor antibody
    • Subtype alpha2 C4 antibody
    see all

Images

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human artery (smooth muscle) tissue labelling aalpha 2C Adrenergic Receptor/ADRA2C with ab140702 after heat-induced antigen retrieval.

References

This product has been referenced in:

  • Tripathi A  et al. Heteromerization of chemokine (C-X-C motif) receptor 4 with a1A/B-adrenergic receptors controls a1-adrenergic receptor function. Proc Natl Acad Sci U S A 112:E1659-68 (2015). Read more (PubMed: 25775528) »
See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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