Key features and details
- Rabbit polyclonal to alpha 2C Adrenergic Receptor/ADRA2C
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
Product nameAnti-alpha 2C Adrenergic Receptor/ADRA2C antibody
See all alpha 2C Adrenergic Receptor/ADRA2C primary antibodies
DescriptionRabbit polyclonal to alpha 2C Adrenergic Receptor/ADRA2C
Tested applicationsSuitable for: WB, IHC-Pmore details
Species reactivityReacts with: Human
Predicted to work with: Mouse, Rat
Synthetic peptide corresponding to Human alpha 2C Adrenergic Receptor/ADRA2C aa 318-409 (C terminal).
Database link: P18825
- HeLa and HepG2 whole cell lysates; Human ES2 xenograft tissue.
This product was previously labelled as alpha 2C Adrenergic Receptor
Storage instructionsShipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage bufferpH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 20% Glycerol
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab151618 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500 - 1/3000. Predicted molecular weight: 50 kDa.|
|IHC-P||1/100 - 1/1000. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.|
RelevanceThe alpha 2C Adrenergic Receptor controls the release of neurotransmitter from central adrenergic neurons and from sympathetic nerves in the heart. This receptor also plays a role in cognitive and behavioral function. Two variants are produced by alternative splicing. Alpha 2C Adrenergic Receptor has been reported extensively in the brain. Blood, corpus cavermosum, kidney, and heart tissues have also been reported to express the protein.
Cellular localizationCell membrane; Multi-pass membrane protein.
- Adra 2c antibody
- ADRA2C antibody
- ADRA2L2 antibody
Anti-alpha 2C Adrenergic Receptor/ADRA2C antibody (ab151618) at 1/1000 dilution + HeLa whole cell
lysate at 30 µg
Predicted band size: 50 kDa
10% SDS PAGE
Immunohistochemical analysis of paraffin-embedded Human ES2 xenograft tissue labeling alpha 2C Adrenergic Receptor/ADRA2C with ab151618 at 1/100 dilution.
ab151618 has been referenced in 2 publications.
- Guan J et al. Higenamine exerts an antispasmodic effect on cold-induced vasoconstriction by regulating the PI3K/Akt, ROS/a2C-AR and PTK9 pathways independently of the AMPK/eNOS/NO axis. Exp Ther Med 18:1299-1308 (2019). PubMed: 31316621
- Weng X et al. Reduced mitochondrial response sensitivity is involved in the anti-apoptotic effect of dexmedetomidine pretreatment in cardiomyocytes. Int J Mol Med 41:2328-2338 (2018). PubMed: 29328437