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    alpha-b-crystallin-antibody-ab166839.pdf

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Signal Transduction Protein Phosphorylation Tyrosine Kinases Other
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Anti-Alpha B Crystallin antibody (ab166839)

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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Alpha B Crystallin antibody (ab166839)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Alpha B Crystallin antibody (ab166839)

Key features and details

  • Rabbit polyclonal to Alpha B Crystallin
  • Suitable for: IHC-P
  • Reacts with: Human
  • Isotype: IgG

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Goat Anti-Rabbit IgG H&L (HRP) (ab205718)
Protein
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Recombinant Human Alpha B Crystallin protein (ab48779)

View more associated products

Overview

  • Product name

    Anti-Alpha B Crystallin antibody
    See all Alpha B Crystallin primary antibodies
  • Description

    Rabbit polyclonal to Alpha B Crystallin
  • Host species

    Rabbit
  • Specificity

    ab166839 does not cross-react with Alpha A crystallin.
  • Tested Applications & Species

    Application Species
    IHC-P
    Human
    See all applications and species data
  • Immunogen

    Synthetic peptide conjugated to KLH corresponding to a region within Human Alpha B Crystallin.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term.
  • Storage buffer

    Constituent: 100% Whole serum
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

    • Signal Transduction
    • Protein Phosphorylation
    • Tyrosine Kinases
    • Other
    • Neuroscience
    • Sensory System
    • Visual system
    • Neuroscience
    • Neurotransmission
    • Receptors / Channels
    • Tyrosine Kinase Receptors
    • Cancer
    • Cancer Metabolism
    • Cellular metabolic process

Associated products

  • Compatible Secondaries

    • Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (ab150077)
    • Goat Anti-Rabbit IgG H&L (HRP) (ab205718)
  • Isotype control

    • Rabbit IgG, polyclonal - Isotype Control (ChIP Grade) (ab171870)
  • Recombinant Protein

    • Recombinant Human Alpha B Crystallin protein (ab48779)

Applications

The Abpromise guarantee

Our Abpromise guarantee covers the use of ab166839 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Guaranteed

Tested applications are guaranteed to work and covered by our Abpromise guarantee.

Predicted

Predicted to work for this combination of applications and species but not guaranteed.

Incompatible

Does not work for this combination of applications and species.

Application Species
IHC-P
Human
Application Abreviews Notes
IHC-P
1/200.
Notes
IHC-P
1/200.

Target

  • Function

    May contribute to the transparency and refractive index of the lens.
  • Tissue specificity

    Lens as well as other tissues.
  • Involvement in disease

    Defects in CRYAB are the cause of myofibrillar alpha-B crystallin-related (MFM-CRYAB) [MIM:608810]. A neuromuscular disorder that results in weakness of the proximal and distal limb muscles, weakness of the neck, velopharynx and trunk muscles, hypetrophic cardiomyopathy, and cataract in a subset of patients.
  • Sequence similarities

    Belongs to the small heat shock protein (HSP20) family.
  • Cellular localization

    Cytoplasm. Nucleus. Translocates to the nucleus during heat shock and resides in sub-nuclear structures known as SC35 speckles or nuclear splicing speckles.
  • Target information above from: UniProt accession P02511 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt
  • Database links

    • Entrez Gene: 1410 Human
    • Omim: 123590 Human
    • SwissProt: P02511 Human
    • Unigene: 53454 Human
    • Alternative names

      • AACRYA antibody
      • Alpha B crystallin antibody
      • Alpha crystallin B chain antibody
      • Alpha(B)-crystallin antibody
      • Alpha-crystallin B chain antibody
      • CRYA2 antibody
      • Cryab antibody
      • CRYAB_HUMAN antibody
      • Crystallin alpha B antibody
      • Crystallin alpha polypeptide 2 antibody
      • CTPP2 antibody
      • Heat shock 20 kD like protein antibody
      • Heat shock protein beta 5 antibody
      • Heat shock protein beta-5 antibody
      • HspB5 antibody
      • Renal carcinoma antigen NY REN 27 antibody
      • Renal carcinoma antigen NY-REN-27 antibody
      • Rosenthal fiber component antibody
      see all

    Images

    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Alpha B Crystallin antibody (ab166839)
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Alpha B Crystallin antibody (ab166839)
      Immunohistochemical analysis of Formalin-fixed, paraffin-embedded Human prostate nerve tissue labeling Alpha B crystallin with ab166839 at 1/200 dilution.
    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Alpha B Crystallin antibody (ab166839)
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Alpha B Crystallin antibody (ab166839)
      Immunohistochemical analysis of Formalin-fixed, paraffin-embedded Human brain cortex tissue labeling Alpha B crystallin with ab166839 at 1/200 dilution.

    Protocols

    • Immunohistochemistry protocols

    Click here to view the general protocols

    Datasheets and documents

    • Datasheet
  • References (0)

    Publishing research using ab166839? Please let us know so that we can cite the reference in this datasheet.

    ab166839 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

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