Key features and details
- Goat polyclonal to alpha Defensin 1
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
Product nameAnti-alpha Defensin 1 antibody
See all alpha Defensin 1 primary antibodies
DescriptionGoat polyclonal to alpha Defensin 1
Tested applicationsSuitable for: WB, IHC-Pmore details
Species reactivityReacts with: Human
Synthetic peptide corresponding to Human alpha Defensin 1 (internal sequence) conjugated to keyhole limpet haemocyanin.
(Peptide available as
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We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
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Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
Storage bufferpH: 7.30
Preservative: 0.02% Sodium azide
Constituents: 99% Tris buffered saline, 0.5% BSA
Concentration information loading...
PurityProtein G purified
Our Abpromise guarantee covers the use of ab122884 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||Use a concentration of 1 - 3 µg/ml. Detects a band of approximately 10 kDa (predicted molecular weight: 10 kDa).|
|IHC-P||Use a concentration of 3.75 µg/ml.|
FunctionDefensin 1 and defensin 2 have antibacterial, fungicide and antiviral activities. Has antimicrobial activity against Gram-negative and Gram-positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane.
Sequence similaritiesBelongs to the alpha-defensin family.
- Information by UniProt
- alpha 1 antibody
- DEF1 antibody
- DEF1_HUMAN antibody
Anti-alpha Defensin 1 antibody (ab122884) at 2 µg/ml + Human spleen lysate at 35 µg
Developed using the ECL technique.
Predicted band size: 10 kDa
Additional bands at: 20 kDa. We are unsure as to the identity of these extra bands.
An additional band of unknown identity was also consistently observed at 20kDa. This band was successfully blocked by incubation with the immunizing peptide.
ab122884, at 3.75 µg/ml, staining alpha Defensin 1 in Formalin-fixed, Paraffin-embedded Human Thymus (Myeloid Cells) tissue by Immunohistochemistry.
ab122884 has been referenced in 2 publications.
- Paulin N et al. Human Neutrophil Peptide 1 Limits Hypercholesterolemia-induced Atherosclerosis by Increasing Hepatic LDL Clearance. EBioMedicine 16:204-211 (2017). IHC-Fr . PubMed: 28111237
- Bian F et al. Nascent proteomes in peripheral blood mononuclear cells as a novel source for biomarker discovery in human stroke. Stroke 45:1177-9 (2014). PubMed: 24558093