Overview

  • Product name

    Anti-alpha Defensin 1 antibody
    See all alpha Defensin 1 primary antibodies
  • Description

    Rabbit polyclonal to alpha Defensin 1
  • Host species

    Rabbit
  • Specificity

    ab134706 detects endogenous levels of alpha 1 Defensin.
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Synthetic peptide derived from the internal region of Human alpha Defensin 1

  • Positive control

    • human breast carcinoma tissue

Properties

Applications

Our Abpromise guarantee covers the use of ab134706 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function

    Defensin 1 and defensin 2 have antibacterial, fungicide and antiviral activities. Has antimicrobial activity against Gram-negative and Gram-positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane.
  • Sequence similarities

    Belongs to the alpha-defensin family.
  • Cellular localization

    Secreted.
  • Information by UniProt
  • Database links

  • Alternative names

    • alpha 1 antibody
    • DEF1 antibody
    • DEF1_HUMAN antibody
    • DEFA1 antibody
    • DEFA1B antibody
    • DEFA2 antibody
    • Defensin 1 antibody
    • Defensin antibody
    • Defensin, alpha 1 antibody
    • Defensin, alpha 1, myeloid related sequence antibody
    • Defensin, alpha 2 antibody
    • HNP-1 antibody
    • HNP-2 antibody
    • HNP1 antibody
    • HP-1 antibody
    • HP-2 antibody
    • HP1 antibody
    • HP2 antibody
    • MRS antibody
    • Myeloid related sequence antibody
    • Neutrophil defensin 1 antibody
    • Neutrophil defensin 2 antibody
    see all

Images

  • Immunohistochemical labelling of paraffin embedded human breast carcinoma tissue with ab134706 at 1/50 dilution

References

ab134706 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

Answer

The mouse and human defensin alpha 1 proteins does not have homology required for antibody cross reactivity so we can not confirm the antibody ab122884 will detect mouse protein as well. We advice customer looking for mouse specific antibody only because we don't think any of anti human antibody would cross-react with mouse protein.

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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