Key features and details
- Rabbit polyclonal to alpha MSH
- Suitable for: IHC-Fr
- Reacts with: Mouse, Rat, Guinea pig
- Isotype: IgG
Product nameAnti-alpha MSH antibody
See all alpha MSH primary antibodies
DescriptionRabbit polyclonal to alpha MSH
Tested applicationsSuitable for: IHC-Frmore details
Species reactivityReacts with: Mouse, Rat, Guinea pig
Synthetic Human MSH alpha conjugated to Bovine thyroglobulin by a Glutaraldehyde linker (P01189).
- Rat pituitary gland tissue.
General notesFor long-term storage, store lyophilized antibody until ready to use at -15º C or lower. After reconstitution, use immediately or refrigerate at 2º-8º C up to 2 days. For long-term storage, appropriately aliquot antibody to avoid repeated freeze/thaw cycles and freeze at -15° C or lower
FormLyophilized:Do not reconstitute until ready to use since the product is most stable when lyophilized. Reconstitute with 100 µL of distilled or deionized water. If desired, dilute with PBS or Tris buffer at a dilution no higher than 1/10.
Storage instructionsShipped at 4°C. Please see notes section.
Storage bufferPreservative: 0.09% Sodium azide
Constituent: 99% Whole serum
Concentration information loading...
Our Abpromise guarantee covers the use of ab123811 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-Fr||1/4000 - 1/6000. in PBS/0.3% Triton X-100 using Bn/Av-HRP technique. Use 4% paraformaldehyde for Fixation and post-fixation.|
RelevanceMelanocyte-stimulating hormone belongs to a group called the melanocortins. This group includes ACTH, alpha-MSH, beta-MSH and gamma-MSH; these peptides are all cleavage products of a large precursor peptide called pro-opiomelanocortin (POMC). Alpha-MSH is the most important melanocortin for pigmentation. It increases the pigmentation of skin by increasing melanin production in melanocytes.
- Alpha MSH antibody
- Melanotropin alpha antibody
- POMC antibody
- proopiomelanocortin antibody
ab123811 has been referenced in 4 publications.
- Hojo M et al. A histopathological analysis of spontaneous neoplastic and non-neoplastic lesions in aged male RccHan:WIST rats. J Toxicol Pathol 33:47-55 (2020). PubMed: 32051666
- Gao Y et al. Deficiency of leptin receptor in myeloid cells disrupts hypothalamic metabolic circuits and causes body weight increase. Mol Metab 7:155-160 (2018). IHC-P ; Mouse . PubMed: 29174000
- Pravdivyi I et al. Progressive postnatal decline in leptin sensitivity of arcuate hypothalamic neurons in the Magel2-null mouse model of Prader-Willi syndrome. Hum Mol Genet 24:4276-83 (2015). ICC/IF ; Mouse . PubMed: 25926624
- Schmid T et al. Loss of NSCL-2 in gonadotropin releasing hormone neurons leads to reduction of pro-opiomelanocortin neurons in specific hypothalamic nuclei and causes visceral obesity. J Neurosci 33:10459-70 (2013). ICC/IF ; Mouse . PubMed: 23785158