Key features and details
- Rabbit polyclonal to alpha smooth muscle Actin
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
Product nameAnti-alpha smooth muscle Actin antibody
See all alpha smooth muscle Actin primary antibodies
DescriptionRabbit polyclonal to alpha smooth muscle Actin
Tested applicationsSuitable for: IHC-Pmore details
Species reactivityReacts with: Human
Synthetic peptide within Human alpha smooth muscle Actin aa 1-100 (N terminal). The exact sequence is proprietary.
Database link: P62736
- Human colon and small intestine tissues.
This product is FOR RESEARCH USE ONLY. For commercial use, please contact firstname.lastname@example.org.The user must validate any other storage conditions.
Storage instructionsShipped at 4°C. Store at +4°C. Do Not Freeze.
Storage bufferpH: 7.60
Preservative: 0.1% Sodium azide
Constituents: PBS, 1% BSA
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab125044 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
FunctionActins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
Involvement in diseaseDefects in ACTA2 are the cause of aortic aneurysm familial thoracic type 6 (AAT6) [MIM:611788]. AATs are characterized by permanent dilation of the thoracic aorta usually due to degenerative changes in the aortic wall. They are primarily associated with a characteristic histologic appearance known as 'medial necrosis' or 'Erdheim cystic medial necrosis' in which there is degeneration and fragmentation of elastic fibers, loss of smooth muscle cells, and an accumulation of basophilic ground substance.
Sequence similaritiesBelongs to the actin family.
Cellular localizationCytoplasm > cytoskeleton.
- Information by UniProt
- a actin antibody
- AAT6 antibody
- ACTA_HUMAN antibody
ab125044 has been referenced in 2 publications.
- Russell OM et al. Preferential amplification of a human mitochondrial DNA deletion in vitro and in vivo. Sci Rep 8:1799 (2018). PubMed: 29379065
- Mao Y et al. Dimensions of the ciliary muscles of Brücke, Müller and Iwanoff and their associations with axial length and glaucoma. Graefes Arch Clin Exp Ophthalmol 256:2165-2171 (2018). PubMed: 30112579