Key features and details
- Rabbit polyclonal to ALR/HPO
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
Product nameAnti-ALR/HPO antibody
See all ALR/HPO primary antibodies
DescriptionRabbit polyclonal to ALR/HPO
Tested applicationsSuitable for: WB, IHC-Pmore details
Species reactivityReacts with: Human
Recombinant fragment within Human ALR/HPO (C terminal). The exact sequence is proprietary.
Database link: P55789
- MCF7, 293T and HepG2 cell lysates
This product was previously labelled as ALR
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Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.40
Preservative: 0.02% Sodium azide
Constituents: 49% PBS, 50% Glycerol (glycerin, glycerine), 0.87% Sodium chloride
PBS is without Mg2+ and Ca2+
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab196498 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500 - 1/2000. Predicted molecular weight: 23 kDa.|
|IHC-P||1/50 - 1/200.|
FunctionIsoform 1: FAD-dependent sulfhydryl oxidase. Within the mitochondrial intermembrane space, participates in a chain of disulfide exchange reactions with MIA40, that generate disulfide bonds in a number of resident proteins with twin Cx3C and Cx9C motifs.
Isoform 2: May act as an autocrine hepatotrophic growth factor promoting liver regeneration.
Tissue specificityUbiquitously expressed. Highest expression in the testis and liver and low expression in the muscle.
Involvement in diseaseDefects in GFER are a cause of mitochondrial progressive myopathy with congenital cataract hearing loss and developmental delay (MPMCHD) [MIM:613076]; also called combined mitochondrial complex deficiency.
Sequence similaritiesContains 1 ERV/ALR sulfhydryl oxidase domain.
Cellular localizationMitochondrion intermembrane space and Cytoplasm. Secreted.
- Information by UniProt
- ALR_HUMAN antibody
- Augmenter of liver regeneration antibody
- ERV1 antibody
ab196498 has not yet been referenced specifically in any publications.