Key features and details
- Rabbit polyclonal to ALR/HPO
- Suitable for: IHC-P, WB
- Reacts with: Human
- Isotype: IgG
Product nameAnti-ALR/HPO antibody
See all ALR/HPO primary antibodies
DescriptionRabbit polyclonal to ALR/HPO
Tested applicationsSuitable for: IHC-P, WBmore details
Species reactivityReacts with: Human
Predicted to work with: Mouse, Rat
- Mouse liver lysate; Human colon cancer tissue.
This product was previously labelled as ALR
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In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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FormLyophilized:Reconstitute in 200ul sterile H2O.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 98% PBS, 1% BSA
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab205282 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||1/100 - 1/500.|
|WB||1/200 - 1/1000. Detects a band of approximately 23 kDa (predicted molecular weight: 15, 23 kDa).|
FunctionIsoform 1: FAD-dependent sulfhydryl oxidase. Within the mitochondrial intermembrane space, participates in a chain of disulfide exchange reactions with MIA40, that generate disulfide bonds in a number of resident proteins with twin Cx3C and Cx9C motifs.
Isoform 2: May act as an autocrine hepatotrophic growth factor promoting liver regeneration.
Tissue specificityUbiquitously expressed. Highest expression in the testis and liver and low expression in the muscle.
Involvement in diseaseDefects in GFER are a cause of mitochondrial progressive myopathy with congenital cataract hearing loss and developmental delay (MPMCHD) [MIM:613076]; also called combined mitochondrial complex deficiency.
Sequence similaritiesContains 1 ERV/ALR sulfhydryl oxidase domain.
Cellular localizationMitochondrion intermembrane space and Cytoplasm. Secreted.
- Information by UniProt
- ALR_HUMAN antibody
- Augmenter of liver regeneration antibody
- ERV1 antibody
Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human colon cancer tissue labeling ALR/HPO with ab205282 at 1/100 dilution.
Anti-ALR/HPO antibody (ab205282) at 1/500 dilution + Mouse liver lysate
Predicted band size: 15, 23 kDa
Observed band size: 23 kDa why is the actual band size different from the predicted?
ab205282 has not yet been referenced specifically in any publications.