Alternariol monomethyl ether, antifungal phytotoxic compound (ab144176)

Overview

  • Product name

    Alternariol monomethyl ether, antifungal phytotoxic compound
  • Description

    Antifungal phytotoxic compound
  • Biological description

    Antifungal phytotoxic compound. Inhibits electron transport chain in chloroplasts. Possesses DNA strand-breaking activity. Inhibits topoisomerase IIα activity. Active in vitro.

    See similar compound
  • Purity

    > 98%
  • CAS Number

    26894-49-5
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    3,7-Dihydroxy-9-methoxy-1-methylbenzo[c]chromen-6-one
  • Molecular weight

    272.25
  • Molecular formula

    C15H12O5
  • PubChem identifier

    5360741
  • Storage instructions

    Store at +4°C. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in ethanol
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CC1=CC(=CC2=C1C3=CC(=CC(=C3C(=O)O2)O)OC)O
  • Source

    Alternaria sp.

References

This product has been referenced in:

  • Demuner AJ  et al. The fungal phytotoxin alternariol 9-methyl ether and some of its synthetic analogues inhibit the photosynthetic electron transport chain. J Nat Prod 76:2234-45 (2013). Read more (PubMed: 24245962) »
  • Fehr M  et al. Alternariol acts as a topoisomerase poison, preferentially affecting the IIalpha isoform. Mol Nutr Food Res 53:441-51 (2009). Read more (PubMed: 18727009) »
  • Pfeiffer E  et al. Novel oxidative in vitro metabolites of the mycotoxins alternariol and alternariol methyl ether. Mol Nutr Food Res 51:307-16 (2007). Read more (PubMed: 17340575) »

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