Overview

  • Product name

    Altretamine, Antineoplastic agent
  • Description

    Antineoplastic agent
  • Biological description

    Antineoplastic agent. Active in ovarian cancer, lymphomas, bronchogenic carcinoma, and carcinoma of the breast.
  • Purity

    > 98%
  • CAS Number

    645-05-6
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    N,N,N′,N′,N′′,N′′-Hexamethyl-1,3,5-triazine-2,4,6-triamine
  • Molecular weight

    210.28
  • Molecular formula

    C9H18N6
  • PubChem identifier

    2123
  • Storage instructions

    Store at Room Temperature. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in DMSO to 50 mM and in ethanol to 100 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CN(C)C1=NC(=NC(=N1)N(C)C)N(C)C
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:

  • Kelner MJ  et al. Synergy of irofulven in combination with other DNA damaging agents: synergistic interaction with altretamine, alkylating, and platinum-derived agents in the MV522 lung tumor model. Cancer Chemother Pharmacol 63:19-26 (2008). Read more (PubMed: 18305940) »
  • Damia G & D'Incalci M Clinical pharmacokinetics of altretamine. Clin Pharmacokinet 28:439-48 (1995). Read more (PubMed: 7656502) »

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