Key features and details
- Potent, selective CB2 agonist
- CAS Number: 444912-48-5
- Purity: > 97%
- Soluble in DMSO to 10 mM and in ethanol to 10 mM
- Form / State: Solid
- Source: Synthetic
Product nameAM1241, CB2 agonist
DescriptionPotent, selective CB2 agonist
Biological descriptionPotent, selective CB2 agonist (Ki = 7.1 nM). Efficacious in vivo, broad-spectrum antinociceptive effects.
Chemical name(2-Iodo-5-nitrophenyl) [1-[(1-methyl-2-piperidinyl)methyl]-1H-indol-3-yl]methanone
Storage instructionsStore at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months.
Solubility overviewSoluble in DMSO to 10 mM and in ethanol to 10 mM
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab120934 has been referenced in 2 publications.
- Li MH et al. Compensatory Activation of Cannabinoid CB2 Receptor Inhibition of GABA Release in the Rostral Ventromedial Medulla in Inflammatory Pain. J Neurosci 37:626-636 (2017). Rat . PubMed: 28100744
- Niu J et al. Activation of dorsal horn cannabinoid CB2 receptor suppresses the expression of P2Y12and P2Y13receptors in neuropathic pain rats. J Neuroinflammation 14:185 (2017). PubMed: 28899427