AMD 3465 hexahydrobromide, CXCR4 antagonist (ab120809)

Overview

  • Product name

    AMD 3465 hexahydrobromide, CXCR4 antagonist
  • Description

    Potent and selective CXCR4 antagonist
  • Biological description

    Potent and selective CXCR4 antagonist. Shows 8-fold greater affinity than AMD 3100 (ab120718). Potent HIV entry inhibitor (IC50 = ~10 nM). Additionally mobilizes stem cells in vivo.
  • Purity

    > 97%
  • CAS Number

    185991-07-5
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    N-[[4-(1,4,8,11-Tetraazacyclotetradec-1-ylmethyl)phenyl]methyl]-2-pyridinemethanamine hexahydrobromide
  • Molecular weight

    896.08
  • Molecular formula

    C24H38N6.6HBr
  • PubChem identifier

    483559
  • Storage instructions

    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in water to 50 mM and in DMSO to 25 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    Br.Br.Br.Br.Br.Br.C3NCCCNCCN(Cc2ccc(CNCc1ccccn1)cc2)CCCNC3
  • Source

    Synthetic

References

ab120809 has not yet been referenced specifically in any publications.

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