Key features and details
- Rabbit polyclonal to AMG
- Suitable for: WB
- Reacts with: Mouse, Human
- Isotype: IgG
Product nameAnti-AMG antibody
See all AMG primary antibodies
DescriptionRabbit polyclonal to AMG
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Mouse, Human
Predicted to work with: Monkey
Recombinant fragment corresponding to Human AMG aa 1-191.
Database link: Q99217
This product was previously labelled as AMELX
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Storage instructionsShipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage bufferpH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 79.99% PBS, 20% Glycerol (glycerin, glycerine)
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab153915 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500 - 1/3000. Predicted molecular weight: 22 kDa.|
FunctionPlays a role in biomineralization. Seems to regulate the formation of crystallites during the secretory stage of tooth enamel development. Thought to play a major role in the structural organization and mineralization of developing enamel.
Involvement in diseaseDefects in AMELX are the cause of amelogenesis imperfecta hypoplastic type 1 (AIH1) [MIM:301200]. AIH1 is a X-linked defect of dental enamel formation. Teeth have only a thin layer of enamel with normal hardness. The thinness of the enamel makes the teeth appear small.
Sequence similaritiesBelongs to the amelogenin family.
Developmental stageTransiently but abundantly expressed by ameloblasts during tooth development. Amelogenin is the predominant protein in developing dental enamel.
Cellular localizationSecreted > extracellular space > extracellular matrix.
- Information by UniProt
- AI1E antibody
- AIH1 antibody
- ALGN antibody
ab153915 has been referenced in 2 publications.
- Aryal YP et al. An endoplasmic reticulum stress regulator, Tmbim6, modulates secretory stage of mice molar. J Cell Physiol N/A:N/A (2019). PubMed: 30963569
- Pandya M et al. Intravesicular Phosphatase PHOSPHO1 Function in Enamel Mineralization and Prism Formation. Front Physiol 8:805 (2017). IHC-P ; Mouse . PubMed: 29089903