Key features and details
- Rabbit polyclonal to AMG
- Suitable for: WB, ELISA
- Reacts with: Recombinant fragment
- Isotype: IgG
Product nameAnti-AMG antibody
See all AMG primary antibodies
DescriptionRabbit polyclonal to AMG
Tested applicationsSuitable for: WB, ELISAmore details
Species reactivityReacts with: Recombinant fragment
Predicted to work with: Mouse, Rat
Synthetic peptide corresponding to Mouse AMG (N terminal).
This product was previously labelled as AMELX
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage bufferPreservative: 0.1% Sodium azide
Constituents: 50% Glycerol, PBS
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab54507 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||Use a concentration of 1 µg/ml. Predicted molecular weight: 22 kDa. for 2 hours. This antibody has been tested in Western blot against the recombinant peptide used as an immunogen. We have no data on detection of endogenous protein.|
|ELISA||Use at an assay dependent dilution.|
FunctionPlays a role in biomineralization. Seems to regulate the formation of crystallites during the secretory stage of tooth enamel development. Thought to play a major role in the structural organization and mineralization of developing enamel.
Involvement in diseaseDefects in AMELX are the cause of amelogenesis imperfecta hypoplastic type 1 (AIH1) [MIM:301200]. AIH1 is a X-linked defect of dental enamel formation. Teeth have only a thin layer of enamel with normal hardness. The thinness of the enamel makes the teeth appear small.
Sequence similaritiesBelongs to the amelogenin family.
Developmental stageTransiently but abundantly expressed by ameloblasts during tooth development. Amelogenin is the predominant protein in developing dental enamel.
Cellular localizationSecreted > extracellular space > extracellular matrix.
- Information by UniProt
- AI1E antibody
- AIH1 antibody
- ALGN antibody
ab54507 has been referenced in 3 publications.
- Zhang B et al. The Role of Epithelial Stat3 in Amelogenesis during Mouse Incisor Renewal. Cells Tissues Organs 205:63-71 (2018). PubMed: 29550820
- Mazumder P et al. Amelogenin-Ameloblastin Spatial Interaction around Maturing Enamel Rods. J Dent Res 95:1042-8 (2016). PubMed: 27146703
- Lacruz RS et al. Identification of novel candidate genes involved in mineralization of dental enamel by genome-wide transcript profiling. J Cell Physiol 227:2264-75 (2012). PubMed: 21809343