Key features and details
- Rabbit polyclonal to AMHR2
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
Product nameAnti-AMHR2 antibody
See all AMHR2 primary antibodies
DescriptionRabbit polyclonal to AMHR2
Tested applicationsSuitable for: WB, IHC-Pmore details
Species reactivityReacts with: Human
Predicted to work with: Mouse, Rat, Rabbit
Recombinant fragment corresponding to Human AMHR2 aa 207-440. BC126316.
QVIREGGHAVVWAGQLQGKLVAIKAFPPRSVAQFQAERALYELPGLQHDH IVRFITASRGGPGRLLSGPLLVLELHPKGSLCHYLTQYTSDWGSSLRMAL SLAQGLAFLHEERWQNGQYKPGIAHRDLSSQNVLIREDGSCAIGDLGLAL VLPGLTQPPAWTPTQPQGPAAIMEAGTQRYMAPELLDKTLDLQDWGMALR RADIYSLALLLWEILSRCPDLRPDSSPPPFQLAY
Database link: Q16671
- HEK293, HEK293T and MCF7 cell lysates. Human fetal testis tissue.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferPreservative: 0.02% Sodium azide
Constituent: 1% BSA
Concentration information loading...
PurityProtein A purified
Our Abpromise guarantee covers the use of ab197148 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/1000 - 1/2000. Predicted molecular weight: 63 kDa.|
|IHC-P||1/100 - 1/500.|
FunctionOn ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for anti-Muellerian hormone.
Involvement in diseaseDefects in AMHR2 are the cause of persistent Muellerian duct syndrome type 2 (PMDS2) [MIM:261550]. PMDS2 is a form of male pseudohermaphroditism characterized by a failure of Muellerian duct regression in otherwise normal males.
Sequence similaritiesBelongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
Contains 1 protein kinase domain.
- Information by UniProt
- AMH type II receptor antibody
- AMHR antibody
- AMHR2 antibody
All lanes : Anti-AMHR2 antibody (ab197148) at 1/1000 dilution
Lane 1 : HEK293 cell lysate
Lane 2 : 293T cell lysate
Lane 3 : MCF7 cell lysate
Predicted band size: 63 kDa
Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human fetal testis tissue labeling AMHR2 with ab197148 at 1/100 dilution.
ab197148 has not yet been referenced specifically in any publications.