Recombinant
RabMAb

Anti-AMHR2 antibody [EPR12225] (ab174311)

Overview

  • Product name
    Anti-AMHR2 antibody [EPR12225]
    See all AMHR2 primary antibodies
  • Description
    Rabbit monoclonal [EPR12225] to AMHR2
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WBmore details
    Unsuitable for: Flow Cyt,ICC/IF,IHC-P or IP
  • Species reactivity
    Reacts with: Mouse, Human
    Does not react with: Rat
  • Immunogen

    Synthetic peptide within Human AMHR2 aa 50-150 (Cysteine residue). The exact sequence is proprietary.
    Database link: Q16671

  • Positive control
    • NIH:OVCAR-3; SK-OV-3 and Human placenta lysates
  • General notes

     

     

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

    This product is a recombinant rabbit monoclonal antibody.

Properties

Applications

Our Abpromise guarantee covers the use of ab174311 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/5000. Predicted molecular weight: 63 kDa.
  • Application notes
    Is unsuitable for Flow Cyt,ICC/IF,IHC-P or IP.
  • Target

    • Function
      On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for anti-Muellerian hormone.
    • Involvement in disease
      Defects in AMHR2 are the cause of persistent Muellerian duct syndrome type 2 (PMDS2) [MIM:261550]. PMDS2 is a form of male pseudohermaphroditism characterized by a failure of Muellerian duct regression in otherwise normal males.
    • Sequence similarities
      Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
      Contains 1 protein kinase domain.
    • Cellular localization
      Membrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • AMH type II receptor antibody
      • AMHR antibody
      • AMHR2 antibody
      • AMHR2_HUMAN antibody
      • Anti Mullerian hormone receptor, type II antibody
      • Anti-Muellerian hormone type II receptor antibody
      • Anti-Muellerian hormone type-2 receptor antibody
      • MGC141312 antibody
      • MIS type II receptor antibody
      • MISR2 antibody
      • MISRII antibody
      • MRII antibody
      • Muellerian hormone type 2 receptor antibody
      • Muellerian hormone type II receptor antibody
      • Muellerian inhibiting substance type II receptor antibody
      • Mullerian hormone receptor type II antibody
      • Mullerian inhibiting substance type II receptor antibody
      see all

    Images

    • All lanes : Anti-AMHR2 antibody [EPR12225] (ab174311) at 1/1000 dilution

      Lane 1 : NIH:OVCAR-3 cell lysate
      Lane 2 : SK-OV-3 cell lysate
      Lane 3 : Human placenta lysate

      Lysates/proteins at 10 µg per lane.

      Predicted band size: 63 kDa

    References

    ab174311 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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