Amidopyrine (Aminophenazone), cytochrome P-450 metabolic activity marker (ab143347)

Overview

  • Product name

    Amidopyrine (Aminophenazone), cytochrome P-450 metabolic activity marker
  • Description

    Non-opioid analgesic agent. Cytochrome P-450 metabolic activity marker.
  • Alternative names

    • Aminophenazone
    • Aminopyrine
  • Biological description

    Non-opioid analgesic agent. Cytochrome P-450 metabolic activity marker. Inhibits CNS prostaglandin synthesis. Shows analgesic, anti-inflammatory and antipyretic effects in vivo. Orally active.
  • Purity

    > 99%
  • CAS Number

    58-15-1
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    4-(Dimethylamino)-1,5-dimethyl-2-phenylpyrazol-3-one
  • Molecular weight

    231.29
  • Molecular formula

    C13H17N3O
  • PubChem identifier

    6009
  • Storage instructions

    Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in DMSO
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Toxic, refer to SDS for further information.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CC1=C(C(=O)N(N1C)C2=CC=CC=C2)N(C)C
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:

  • Jasiecka A  et al. Pharmacological characteristics of metamizole. Pol J Vet Sci 17:207-14 (2014). Read more (PubMed: 24724493) »
  • Latos P & Wojtczak AB Use of the glucose oxidase/peroxidase method for glucose assay leads to overestimation of the inhibition of gluconeogenesis by aminopyrine. Biochim Biophys Acta 991:152-4 (1989). Read more (PubMed: 2713417) »
  • Imaoka S  et al. Aminopyrine metabolism by multiple forms of cytochrome P-450 from rat liver microsomes: simultaneous quantitation of four aminopyrine metabolites by high-performance liquid chromatography. Arch Biochem Biophys 265:159-70 (1988). Read more (PubMed: 3415241) »

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