Key features and details
- Potent, competetive dihydrofolate reductase inhibitor
- CAS Number: 54-62-6
- Purity: > 98%
- Soluble in DMSO
- Form / State: Solid
- Source: Synthetic
Product nameAminopterin, dihydrofolate reductase inhibitor
DescriptionPotent, competetive dihydrofolate reductase inhibitor
Biological descriptionPotent, competitive dihydrofolate reductase inhibitor. Shows antineoplastic and immunosuppressive effects in vivo. Orally active.
Chemical name2-[[4-[(2,4-Diaminopteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid
Storage instructionsStore at Room Temperature. The product can be stored for up to 12 months.
Solubility overviewSoluble in DMSO
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
- Pathways and Processes
- Metabolic signaling pathways
- Nucleotide metabolism
- Molecular processes
- Mitochondrial transcription
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab142394 has not yet been referenced specifically in any publications.