Ammonium Glycyrrhizinate (Glycyram), cytoprotective agent (ab143162)

Overview

  • Product name

    Ammonium Glycyrrhizinate (Glycyram), cytoprotective agent
  • Description

    Glycyrrhizic acid salt. Cytoprotective agent.
  • Alternative names

    • Glycyram
  • Biological description

    Glycyrrhizic acid (ab143127) salt. Cytoprotective agent. Inhibits ROS production. Shows anti-inflammatory and antinociceptive effects in vivo. Orally active.
  • CAS Number

    53956-04-0
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    (2S,3S,4S,5R,6R)-6-[(2S,3R,4S,5S,6S)-2-[[(3S,4aR,6aR,6bS,8aS,11S,12aR,14aR,14bS)-11-Carboxy-4,4,6a,6b,8a,11,14b-heptamethyl-14-oxo-2,3,4a,5,6,7,8,9,10,12,12a,14a-dodecahydro-1H-picen-3-yl]oxy]-6-carboxy-4,5-dihydroxyoxan-3-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid ammonium salt
  • Molecular weight

    839.96
  • Molecular formula

    C42H65NO16
  • PubChem identifier

    62074
  • Storage instructions

    Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in DMSO to 100 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CC1(C2CCC3(C(C2(CCC1OC4C(C(C(C(O4)C(=O)O)O)O)OC5C(C(C(C(O5)C(=O)O)O)O)O)C)C(=O)C=C6C3(CCC7(C6CC(CC7)(C)C(=O)O)C)C)C)C.N
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:

  • Marianecci C  et al. Ammonium glycyrrhizinate-loaded niosomes as a potential nanotherapeutic system for anti-inflammatory activity in murine models. Int J Nanomedicine 9:635-51 (2014). Read more (PubMed: 24493924) »
  • Oh HM  et al. Ammonium glycyrrhizinate protects gastric epithelial cells from hydrogen peroxide-induced cell death. Exp Biol Med (Maywood) 234:263-77 (2009). Read more (PubMed: 19144869) »
  • Mantovani A  et al. Teratogenicity study of ammonium glycyrrhizinate in the Sprague-Dawley rat. Food Chem Toxicol 26:435-40 (1988). Read more (PubMed: 3391466) »

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES, NOT FOR USE IN HUMANS"
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