Overview

  • Product name

    Amorolfine Hydrochloride, antifungal agent
  • Description

    Broad spectrum antifungal agent. D14 reductase and D7-D8 isomerase inhibitor.
  • Biological description

    Broad spectrum antifungal agent. D14 reductase and D7-D8 isomerase inhibitor. Selectively blocks ergosterol biosynthesis. Depletes ergosterol and causes ignosterol to accumulate in the fungal cytoplasmic cell membranes in vivo.
  • Purity

    > 96%
  • CAS Number

    78613-38-4
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Ghelardi E  et al. Potential of Ergosterol synthesis inhibitors to cause resistance or cross-resistance in Trichophyton rubrum. Antimicrob Agents Chemother 58:2825-9 (2014). Read more (PubMed: 24614379) »
  • Gao Y  et al. Simultaneous determination of triacetin, acetic ether, butyl acetate and amorolfine hydrochloride in amorolfine liniment by HPLC. Pak J Pharm Sci 25:389-94 (2012). Read more (PubMed: 22459467) »
  • Koch AJ & Holaska JM Loss of emerin alters myogenic signaling and miRNA expression in mouse myogenic progenitors. PLoS One 7:e37262 (2012). Read more (PubMed: 22606356) »

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