Overview

  • Product name

    Anti-Amphiregulin antibody
    See all Amphiregulin primary antibodies
  • Description

    Rabbit polyclonal to Amphiregulin
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-P, ICC/IFmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Recombinant fragment corresponding to Human Amphiregulin aa 107-148.
    Sequence:

    VVKPPQNKTESENTSDKPKRKKKGGKNGKNRRNRKKKNPCNA


    Database link: P15514

  • Positive control

    • IHC-P: Human breast cancer and colon cancer tissues. ICC/IF: HeLa cells.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    pH: 7.40
    Preservative: 0.03% Proclin
    Constituents: PBS, 50% Glycerol
  • Concentration information loading...
  • Purity

    Protein G purified
  • Purification notes

    Purity >95%.
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab234750 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/20 - 1/200.
ICC/IF 1/50 - 1/200.

Target

  • Function

    Bifunctional growth-modulating glycoprotein. Inhibits growth of several human carcinoma cells in culture and stimulates proliferation of human fibroblasts and certain other tumor cells.
  • Sequence similarities

    Belongs to the amphiregulin family.
    Contains 1 EGF-like domain.
  • Cellular localization

    Membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • A REG antibody
    • Amphiregulin antibody
    • Amphiregulin B antibody
    • AR antibody
    • AREG antibody
    • AREG_HUMAN antibody
    • AREGB antibody
    • Colorectum cell derived growth factor antibody
    • Colorectum cell-derived growth factor antibody
    • CRDGF antibody
    • MGC13647 antibody
    • Schwannoma derived growth factor antibody
    • SDGF antibody
    see all

Images

  • HeLa (human epithelial cell line from cervix adenocarcinoma) cells labeling Amphiregulin (green) using ab234750 at 1/100 dilution in ICC/IF, followed by Alexa Fluor 488® congugated Goat Anti-Rabbit IgG (H+L).

  • Paraffin-embedded human colon cancer tissue stained for Amphiregulin using ab234750 at 1/100 dilution in immunohistochemical analysis.

  • Paraffin-embedded human breast cancer tissue stained for Amphiregulin using ab234750 at 1/100 dilution in immunohistochemical analysis.

References

ab234750 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab234750.
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