Anti-AMPK alpha 1 + AMPK alpha 2 antibody [34.2] (ab80039)

Mouse monoclonal AMPK alpha 1 + AMPK alpha 2 antibody [34.2]. Validated in WB, IP, ELISA, IHC and tested in Mouse, Rat, Human, Drosophila melanogaster. Cited in 24 publication(s).

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ab80039 has been referenced in 31 publications.

  • Chauhan AS  et al. STIM2 interacts with AMPK and regulates calcium-induced AMPK activation. FASEB J 33:2957-2970 (2019). PubMed: 30335546
  • Sampedro J  et al. New Insights into the Mechanisms of Action of Topical Administration of GLP-1 in an Experimental Model of Diabetic Retinopathy. J Clin Med 8:N/A (2019). PubMed: 30862093
  • Guo HH  et al. Liver-target nanotechnology facilitates berberine to ameliorate cardio-metabolic diseases. Nat Commun 10:1981 (2019). PubMed: 31040273
  • Zhou XT  et al. Inhibition of autophagy enhances adenosine-induced apoptosis in human hepatoblastoma HepG2 cells. Oncol Rep 41:829-838 (2019). PubMed: 30535464
  • Gao J  et al. Trilobatin Protects Against Oxidative Injury in Neuronal PC12 Cells Through Regulating Mitochondrial ROS Homeostasis Mediated by AMPK/Nrf2/Sirt3 Signaling Pathway. Front Mol Neurosci 11:267 (2018). PubMed: 30104959
  • de Las Heras N  et al. Chronic Exercise Improves Mitochondrial Function and Insulin Sensitivity in Brown Adipose Tissue. Front Physiol 9:1122 (2018). PubMed: 30174613
  • Ilic BB  et al. VHL Dependent Expression of REDD1 and PDK3 Proteins in Clear-cell Renal Cell Carcinoma. J Med Biochem 37:31-38 (2018). PubMed: 30581339
  • Wen Z  et al. Overexpression of miR-185 inhibits autophagy and apoptosis of dopaminergic neurons by regulating the AMPK/mTOR signaling pathway in Parkinson's disease. Mol Med Rep 17:131-137 (2018). PubMed: 29115479
  • Lyu SC  et al. Fyn knockdown inhibits migration and invasion in cholangiocarcinoma through the activated AMPK/mTOR signaling pathway. Oncol Lett 15:2085-2090 (2018). PubMed: 29434909
  • Yang Q  et al. PRKAA1/AMPKa1-driven glycolysis in endothelial cells exposed to disturbed flow protects against atherosclerosis. Nat Commun 9:4667 (2018). PubMed: 30405100
  • Jiang X  et al. Fucoxanthin prevents lipopolysaccharide-induced depressive-like behavior in mice via AMPK- NF-?B pathway. Metab Brain Dis N/A:N/A (2018). PubMed: 30554399
  • Zhu L  et al. Dai-Zong-Fang, A Traditional Chinese Herbal Formula, Ameliorates Insulin Resistance in db/db Mice. Front Physiol 9:224 (2018). PubMed: 29593575
  • Guo H  et al. Astragaloside IV protects against podocyte injury via SERCA2-dependent ER stress reduction and AMPKa-regulated autophagy induction in streptozotocin-induced diabetic nephropathy. Sci Rep 7:6852 (2017). PubMed: 28761152
  • Panisello-Roselló A  et al. The Relevance of the UPS in Fatty Liver Graft Preservation: A New Approach for IGL-1 and HTK Solutions. Int J Mol Sci 18:N/A (2017). PubMed: 29088097
  • Moura CS  et al. Bioactivity of food peptides: biological response of rats to bovine milk whey peptides following acute exercise. Food Nutr Res 61:1290740 (2017). WB ; Rat . PubMed: 28326005
  • Wu H  et al. The Anti-atherosclerotic Effect of Paeonol against Vascular Smooth Muscle Cell Proliferation by Up-regulation of Autophagy via the AMPK/mTOR Signaling Pathway. Front Pharmacol 8:948 (2017). PubMed: 29354055
  • Liang D  et al. Therapeutic efficacy of apelin on transplanted mesenchymal stem cells in hindlimb ischemic mice via regulation of autophagy. Sci Rep 6:21914 (2016). WB ; Mouse . PubMed: 26902855
  • Li J  et al. An obligatory role for neurotensin in high-fat-diet-induced obesity. Nature 533:411-5 (2016). PubMed: 27193687
  • Omura J  et al. Protective Roles of Endothelial AMP-Activated Protein Kinase Against Hypoxia-Induced Pulmonary Hypertension in Mice. Circ Res 119:197-209 (2016). PubMed: 27217398
  • Jiao Y  et al. The Fto Gene Regulates the Proliferation and Differentiation of Pre-Adipocytes in Vitro. Nutrients 8:102 (2016). WB ; Mouse . PubMed: 26907332
  • Ye T  et al. Isoorientin induces apoptosis, decreases invasiveness, and downregulates VEGF secretion by activating AMPK signaling in pancreatic cancer cells. Onco Targets Ther 9:7481-7492 (2016). WB ; Human . PubMed: 28003763
  • Chen D  et al. Madagascine Induces Vasodilatation via Activation of AMPK. Front Pharmacol 7:435 (2016). WB ; Human . PubMed: 27932979
  • Krawchuk D  et al. Loss of LKB1 leads to impaired epithelial integrity and cell extrusion in the early mouse embryo. J Cell Sci 128:1011-22 (2015). IHC (PFA fixed) ; Mouse . PubMed: 25588837
  • Wagner AE  et al. Epigallocatechin gallate affects glucose metabolism and increases fitness and lifespan in Drosophila melanogaster. Oncotarget 6:30568-78 (2015). WB . PubMed: 26375250
  • Tiwari M  et al. A nonapoptotic role for CASP2/caspase 2: modulation of autophagy. Autophagy 10:1054-70 (2014). PubMed: 24879153
  • Cam M  et al. p53/TAp63 and AKT regulate mammalian target of rapamycin complex 1 (mTORC1) signaling through two independent parallel pathways in the presence of DNA damage. J Biol Chem 289:4083-94 (2014). IP ; Human . PubMed: 24366874
  • Lima VV  et al. Vascular O-GlcNAcylation augments reactivity to constrictor stimuli by prolonging phosphorylated levels of the myosin light chain. Braz J Med Biol Res 47:826-33 (2014). WB ; Rat . PubMed: 25140811
  • Eriksson L & Nyström T Activation of AMP-activated protein kinase by metformin protects human coronary artery endothelial cells against diabetic lipoapoptosis. Cardiovasc Diabetol 13:152 (2014). WB ; Human . PubMed: 25391818
  • Spindler SR  et al. Novel protein kinase signaling systems regulating lifespan identified by small molecule library screening using Drosophila. PLoS One 7:e29782 (2012). WB ; Drosophila melanogaster . PubMed: 22363408
  • Poels J  et al. Autophagy and phagocytosis-like cell cannibalism exert opposing effects on cellular survival during metabolic stress. Cell Death Differ 19:1590-601 (2012). PubMed: 22498699
  • Fu J  et al. trans-(-)-e-Viniferin increases mitochondrial sirtuin 3 (SIRT3), activates AMP-activated protein kinase (AMPK), and protects cells in models of Huntington Disease. J Biol Chem 287:24460-72 (2012). WB . PubMed: 22648412

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