Overview

  • Product name

    Amygdalin, Glycosidic antineoplastic agent
  • Description

    Glycosidic antineoplastic agent
  • Biological description

    Glycosidic antineoplastic agent. Induces apoptosis through the BCL pathway. Inhibits angiogenesis and displays antitumor effects in vivo. Orally active.
  • Purity

    > 98%
  • CAS Number

    29883-15-6
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    2-Phenyl-2-[(1R,2R,3S,4R,5R)-2,3,4-trihydroxy-5-[[(2R,3R,4S,5S,6R)-3,4,
    5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]cyclohexyl]oxyacetonitrile
  • Molecular weight

    457.43
  • Molecular formula

    C21H29NO10
  • PubChem identifier

    16211172
  • Storage instructions

    Store at Room Temperature. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in water to 100mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    C1C(C(C(C(C1OC(C#N)C2=CC=CC=C2)O)O)O)COC3C(C(C(C(O3)CO)O)O)O
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:

  • Chen Y  et al. Amygdalin induces apoptosis in human cervical cancer cell line HeLa cells. Immunopharmacol Immunotoxicol 35:43-51 (2013). Read more (PubMed: 23137229) »
  • Adewusi SR & Oke OL On the metabolism of amygdalin. 1. The LD50 and biochemical changes in rats. Can J Physiol Pharmacol 63:1080-3 (1985). Read more (PubMed: 2932206) »
  • Mirmiranpour H  et al. Amygdalin inhibits angiogenesis in the cultured endothelial cells of diabetic rats. Indian J Pathol Microbiol 55:211-4 (0). Read more (PubMed: 22771646) »

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