Overview

  • Product name

    Angiotensin II (human), Vasoconstrictor peptide
  • Description

    Vasoconstrictor peptide
  • Biological description

    Endogenous peptide involved in body water and electrolyte homeostasis, blood pressure, cyclicity of reproductive hormones and sexual behaviours, and the regulation of pituitary gland hormones.
  • Purity

    > 95%
  • CAS Number

    4474-91-3
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

See all 5 Publications for this product

Customer reviews and Q&As

1-2 of 2 Abreviews or Q&A

We planned to use Angiotensin II in our rat model of diffuse myocardial fibrosis. We implanted 2ml 4 week duration Azlet Osmotic Minipumps (2ml4) intraperitoneally in 300g sprage dawley rats for 3 weeks. The dosing was set to 500ng/kg/min for that time period. After 3 weeks the heart was explanted and fixed in formalin and analyses in cross sections with sirus red staining. Attached is an image showing the fibrosis it induced.

Abcam user community

Verified customer

Submitted May 03 2018

Question
Answer

ab120183 is an endogenous vasoconstrictor peptide (the human version) so will function in the same way as the native peptide. You may find this paper useful - http://www.ncbi.nlm.nih.gov/pubmed/17329311?dopt=Abstract.

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