Anti-Angiotensin II Type 1 Receptor antibody (ab31667)

Overview

  • Product name
    Anti-Angiotensin II Type 1 Receptor antibody
    See all Angiotensin II Type 1 Receptor primary antibodies
  • Description
    Sheep polyclonal to Angiotensin II Type 1 Receptor
  • Host species
    Sheep
  • Specificity
    Highly reactive and specific to human Angiotensin Factor-1 receptor.
  • Tested applications
    Suitable for: ELISA, WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Angiotensin Type I Receptor (Fusion Protein).

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab31667 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA 1/500 - 1/2000.
WB 1/50 - 1/1000. Predicted molecular weight: 40 kDa.

Target

  • Function
    Receptor for angiotensin II. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
  • Tissue specificity
    Liver, lung, adrenal and adrenocortical adenomas.
  • Involvement in disease
    Defects in AGTR1 are a cause of renal tubular dysgenesis (RTD) [MIM:267430]. RTD is an autosomal recessive severe disorder of renal tubular development characterized by persistent fetal anuria and perinatal death, probably due to pulmonary hypoplasia from early-onset oligohydramnios (the Potter phenotype).
  • Sequence similarities
    Belongs to the G-protein coupled receptor 1 family.
  • Post-translational
    modifications
    C-terminal Ser or Thr residues may be phosphorylated.
  • Cellular localization
    Cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • AG2S antibody
    • Agtr 1 antibody
    • Agtr1 antibody
    • AGTR1_HUMAN antibody
    • Agtr1a antibody
    • AGTR1B antibody
    • Ang II antibody
    • Angiotensin II receptor type 1 antibody
    • Angiotensin II type-1 receptor antibody
    • Angiotensin receptor 1 antibody
    • Angiotensin receptor 1B antibody
    • AT 1B antibody
    • AT 1r antibody
    • AT1 antibody
    • At1a antibody
    • AT1AR antibody
    • AT1B antibody
    • AT1BR antibody
    • AT1R antibody
    • AT2R1 antibody
    • AT2R1A antibody
    • AT2R1B antibody
    • HAT1R antibody
    • Type 1 angiotensin II receptor antibody
    • Type 1B angiotensin II receptor antibody
    • Type-1 angiotensin II receptor antibody
    see all

References

ab31667 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

Answer

Thank you for contacting us.

The immunogen for ab31667 is a C-terminal fragment and does not overlap the peptide ab47407. Unfortunately, we do not currently sell any antibodies that can be used with the peptide ab47407.

The only matching antibody and peptides that we currently sell areab91523 and ab91524 for use with ab18801. Unfortunately, these are not validated for use on human samples. If you would like to test ab18801 for use on human samples, I would be happy to offer you our 100% testing discount, which is basically a buy one, get one free. If you purchase ab18801 for full price, test it on human samples, and submit an Abreview with your protocol and results, I will give you a discount code that can be used to receive a free primary antibody on a future order.

I hope this helps, please let me know if you would like to test ab18801 or if you need any additional information or assistance.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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