Angiotensin II Type 1 Receptor peptide (ab176148)
Key features and details
- Suitable for: Blocking
Description
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Product name
Angiotensin II Type 1 Receptor peptide
See all Angiotensin II Type 1 Receptor proteins and peptides -
Animal free
No -
Nature
Synthetic
Associated products
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Corresponding Antibody
Specifications
Our Abpromise guarantee covers the use of ab176148 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
Blocking - Blocking peptide for Anti-Angiotensin II Type 1 Receptor antibody (ab124505)
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Form
Liquid -
Concentration information loading...
Preparation and Storage
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Stability and Storage
Store at -20°C.
pH: 7.20
Preservative: 0.02% Sodium azide
Constituents: PBS, 0.1% bovine serum albumin
General Info
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Alternative names
- AG2S
- Agtr 1
- Agtr1
see all -
Function
Receptor for angiotensin II. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. -
Tissue specificity
Liver, lung, adrenal and adrenocortical adenomas. -
Involvement in disease
Defects in AGTR1 are a cause of renal tubular dysgenesis (RTD) [MIM:267430]. RTD is an autosomal recessive severe disorder of renal tubular development characterized by persistent fetal anuria and perinatal death, probably due to pulmonary hypoplasia from early-onset oligohydramnios (the Potter phenotype). -
Sequence similarities
Belongs to the G-protein coupled receptor 1 family. -
Post-translational
modificationsC-terminal Ser or Thr residues may be phosphorylated. -
Cellular localization
Cell membrane. - Information by UniProt
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab176148 has not yet been referenced specifically in any publications.