Key features and details
- Suitable for: Blocking
Product nameAngiotensin II Type 1 Receptor peptide
See all Angiotensin II Type 1 Receptor proteins and peptides
Our Abpromise guarantee covers the use of ab176148 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Blocking - Blocking peptide for Anti-Angiotensin II Type 1 Receptor antibody (ab124505)
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Preparation and Storage
Stability and Storage
Store at -20°C.
Preservative: 0.02% Sodium azide
Constituents: PBS, 0.1% bovine serum albumin
- Agtr 1
FunctionReceptor for angiotensin II. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
Tissue specificityLiver, lung, adrenal and adrenocortical adenomas.
Involvement in diseaseDefects in AGTR1 are a cause of renal tubular dysgenesis (RTD) [MIM:267430]. RTD is an autosomal recessive severe disorder of renal tubular development characterized by persistent fetal anuria and perinatal death, probably due to pulmonary hypoplasia from early-onset oligohydramnios (the Potter phenotype).
Sequence similaritiesBelongs to the G-protein coupled receptor 1 family.
modificationsC-terminal Ser or Thr residues may be phosphorylated.
Cellular localizationCell membrane.
- Information by UniProt
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab176148 has not yet been referenced specifically in any publications.