Anti-Angiotensin II Type 2 Receptor antibody (ab140704)
- Datasheet
- References
- Protocols
Overview
-
Product name
Anti-Angiotensin II Type 2 Receptor antibody
See all Angiotensin II Type 2 Receptor primary antibodies -
Description
Rabbit polyclonal to Angiotensin II Type 2 Receptor -
Host species
Rabbit -
Specificity
BLAST analysis of the peptide immunogen showed no homology with other human proteins, except GPR65 (63%) and NPFFR2 (44%). -
Tested applications
Suitable for: IHC-Pmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat, Sheep, Horse, Hamster, Cow, Dog, Pig, Monkey, Gorilla, Common marmoset, Bat, Elephant
-
Immunogen
Synthetic 16 amino acids peptide from the internal region of Human Angiotensin II Type 2 Receptor.
-
Positive control
- Human adrenal tissue; Human uterus tissue
Properties
-
Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles. -
Storage buffer
Preservative: 0.1% Sodium azide
Constituent: 99% PBS -
Concentration information loading... -
Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
-
Compatible Secondaries
-
Isotype control
-
Recombinant Protein
Applications
Our Abpromise guarantee covers the use of ab140704 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| IHC-P | Use a concentration of 10 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol. |
Target
-
Function
Receptor for angiotensin II. Cooperates with MTUS1 to inhibit ERK2 activation and cell proliferation. -
Tissue specificity
In adult, highly expressed in myometrium with lower levels in adrenal gland and fallopian tube. Very highly expressed in fetal kidney and intestine. -
Sequence similarities
Belongs to the G-protein coupled receptor 1 family. -
Cellular localization
Cell membrane. - Information by UniProt
-
Database links
- Entrez Gene: 407157 Cow
- Entrez Gene: 403835 Dog
- Entrez Gene: 186 Human
- Entrez Gene: 11609 Mouse
- Entrez Gene: 733586 Pig
- Entrez Gene: 24182 Rat
- Omim: 300034 Human
- SwissProt: P50052 Human
see all -
Alternative names
- AGTR 2 antibody
- Agtr2 antibody
- AGTR2_HUMAN antibody
see all
Images
-
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Angiotensin II Type 2 Receptor antibody (ab140704)Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human uterus tissue labelling Angiotensin II Type 2 Receptor with ab140704 after heat-induced antigen retrieval. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. -
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Angiotensin II Type 2 Receptor antibody (ab140704)Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human adrenal tissue labelling Angiotensin II Type 2 Receptor with ab140704 after heat-induced antigen retrieval. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.
Protocols
References
ab140704 has not yet been referenced specifically in any publications.
