Anti-Angiotensin II Type 2 Receptor antibody (ab140704)
Key features and details
- Rabbit polyclonal to Angiotensin II Type 2 Receptor
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-Angiotensin II Type 2 Receptor antibody
See all Angiotensin II Type 2 Receptor primary antibodies -
Description
Rabbit polyclonal to Angiotensin II Type 2 Receptor -
Host species
Rabbit -
Specificity
BLAST analysis of the peptide immunogen showed no homology with other human proteins, except GPR65 (63%) and NPFFR2 (44%). -
Tested Applications & Species
See all applications and species dataApplication Species IHC-P Human
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Immunogen
Synthetic 16 amino acids peptide from the internal region of Human Angiotensin II Type 2 Receptor.
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Positive control
- Human adrenal tissue; Human uterus tissue
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles. -
Storage buffer
Preservative: 0.1% Sodium azide
Constituent: 99% PBS -
Concentration information loading... -
Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab140704 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Tested applications are guaranteed to work and covered by our Abpromise guarantee.
Predicted to work for this combination of applications and species but not guaranteed.
Does not work for this combination of applications and species.
| Application | Species |
|---|---|
| IHC-P |
Human
|
| All applications |
Mouse
Rat
Sheep
Horse
Hamster
Cow
Dog
Pig
Monkey
Gorilla
Common marmoset
Bat
Elephant
|
| Application | Abreviews | Notes |
|---|---|---|
| IHC-P |
Use a concentration of 10 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
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| Notes |
|---|
|
IHC-P
Use a concentration of 10 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol. |
Target
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Function
Receptor for angiotensin II. Cooperates with MTUS1 to inhibit ERK2 activation and cell proliferation. -
Tissue specificity
In adult, highly expressed in myometrium with lower levels in adrenal gland and fallopian tube. Very highly expressed in fetal kidney and intestine. -
Sequence similarities
Belongs to the G-protein coupled receptor 1 family. -
Cellular localization
Cell membrane. - Information by UniProt
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Database links
- Entrez Gene: 407157 Cow
- Entrez Gene: 403835 Dog
- Entrez Gene: 186 Human
- Entrez Gene: 11609 Mouse
- Entrez Gene: 733586 Pig
- Entrez Gene: 24182 Rat
- Omim: 300034 Human
- SwissProt: P50052 Human
see all -
Alternative names
- AGTR 2 antibody
- Agtr2 antibody
- AGTR2_HUMAN antibody
see all
Images
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Angiotensin II Type 2 Receptor antibody (ab140704)Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human uterus tissue labelling Angiotensin II Type 2 Receptor with ab140704 after heat-induced antigen retrieval. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Angiotensin II Type 2 Receptor antibody (ab140704)Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human adrenal tissue labelling Angiotensin II Type 2 Receptor with ab140704 after heat-induced antigen retrieval. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.
References (0)
ab140704 has not yet been referenced specifically in any publications.
