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Anti-Angiotensin II Type 2 Receptor antibody (ab140704)

  • Datasheet
  • SDS
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Angiotensin II Type 2 Receptor antibody (ab140704)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Angiotensin II Type 2 Receptor antibody (ab140704)

Key features and details

  • Rabbit polyclonal to Angiotensin II Type 2 Receptor
  • Suitable for: IHC-P
  • Reacts with: Human
  • Isotype: IgG

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Overview

  • Product name

    Anti-Angiotensin II Type 2 Receptor antibody
    See all Angiotensin II Type 2 Receptor primary antibodies
  • Description

    Rabbit polyclonal to Angiotensin II Type 2 Receptor
  • Host species

    Rabbit
  • Specificity

    BLAST analysis of the peptide immunogen showed no homology with other human proteins, except GPR65 (63%) and NPFFR2 (44%).
  • Tested Applications & Species

    Application Species
    IHC-P
    Human
    See all applications and species data
  • Immunogen

    Synthetic 16 amino acids peptide from the internal region of Human Angiotensin II Type 2 Receptor.

  • Positive control

    • Human adrenal tissue; Human uterus tissue

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
  • Storage buffer

    Preservative: 0.1% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

    • Signal Transduction
    • Signaling Pathway
    • Lipid Signaling
    • PLC
    • Signal Transduction
    • Signaling Pathway
    • G Protein Signaling
    • GPCR
    • Cardiovascular
    • Atherosclerosis
    • Apoptosis
    • Cardiovascular
    • Blood
    • Blood Pressure regulation

Associated products

  • Compatible Secondaries

    • Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (ab150077)
    • Goat Anti-Rabbit IgG H&L (HRP) (ab205718)
  • Isotype control

    • Rabbit IgG, polyclonal - Isotype Control (ChIP Grade) (ab171870)
  • Recombinant Protein

    • Recombinant Human Angiotensin II Type 2 Receptor protein (ab157871)

Applications

The Abpromise guarantee

Our Abpromise guarantee covers the use of ab140704 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Guaranteed

Tested applications are guaranteed to work and covered by our Abpromise guarantee.

Predicted

Predicted to work for this combination of applications and species but not guaranteed.

Incompatible

Does not work for this combination of applications and species.

Application Species
IHC-P
Human
All applications
Mouse
Rat
Sheep
Horse
Hamster
Cow
Dog
Pig
Monkey
Gorilla
Common marmoset
Bat
Elephant
Application Abreviews Notes
IHC-P
Use a concentration of 10 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
Notes
IHC-P
Use a concentration of 10 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.

Target

  • Function

    Receptor for angiotensin II. Cooperates with MTUS1 to inhibit ERK2 activation and cell proliferation.
  • Tissue specificity

    In adult, highly expressed in myometrium with lower levels in adrenal gland and fallopian tube. Very highly expressed in fetal kidney and intestine.
  • Sequence similarities

    Belongs to the G-protein coupled receptor 1 family.
  • Cellular localization

    Cell membrane.
  • Target information above from: UniProt accession P50052 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt
  • Database links

    • Entrez Gene: 407157 Cow
    • Entrez Gene: 403835 Dog
    • Entrez Gene: 186 Human
    • Entrez Gene: 11609 Mouse
    • Entrez Gene: 733586 Pig
    • Entrez Gene: 24182 Rat
    • Omim: 300034 Human
    • SwissProt: P50052 Human
    • SwissProt: P35374 Mouse
    • SwissProt: Q3US12 Mouse
    • SwissProt: P35351 Rat
    • Unigene: 405348 Human
    • Unigene: 2679 Mouse
    • Unigene: 162367 Rat
    see all
  • Alternative names

    • AGTR 2 antibody
    • Agtr2 antibody
    • AGTR2_HUMAN antibody
    • angiotensin II receptor type 2 antibody
    • Angiotensin II type-2 receptor antibody
    • Angiotensin receptor 2 antibody
    • AT 2 antibody
    • AT2 antibody
    • ATGR 2 antibody
    • ATGR2 antibody
    • MRX 88 antibody
    • MRX88 antibody
    • Type 2 angiotensin II receptor antibody
    • Type-2 angiotensin II receptor antibody
    see all

Images

  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Angiotensin II Type 2 Receptor antibody (ab140704)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Angiotensin II Type 2 Receptor antibody (ab140704)
    Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human uterus tissue labelling Angiotensin II Type 2 Receptor with ab140704 after heat-induced antigen retrieval. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Angiotensin II Type 2 Receptor antibody (ab140704)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Angiotensin II Type 2 Receptor antibody (ab140704)
    Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human adrenal tissue labelling Angiotensin II Type 2 Receptor with ab140704 after heat-induced antigen retrieval. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.

Protocols

  • Immunohistochemistry protocols

Click here to view the general protocols

Datasheets and documents

    • Datasheet
    • SDS
  • References (0)

    Publishing research using ab140704? Please let us know so that we can cite the reference in this datasheet.

    ab140704 has not yet been referenced specifically in any publications.

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