Overview

  • Product name

    Anti-ANKH antibody - C-terminal
    See all ANKH primary antibodies
  • Description

    Rabbit polyclonal to ANKH - C-terminal
  • Host species

    Rabbit
  • Tested applications

    Suitable for: Flow Cyt, IHC-P, WBmore details
  • Species reactivity

    Reacts with: Mouse, Human
  • Immunogen

    Synthetic peptide within Human ANKH aa 464-492 (C terminal) conjugated to Keyhole Limpet Haemocyanin (KLH). The exact sequence is proprietary. NP_473368.1
    Database link: Q9HCJ1

  • Positive control

    • Mouse cerebellum tissue lysate; Human brain cortex tissue; K562 cells.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    Preservative: 0.09% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab211460 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt 1/10 - 1/50.
IHC-P 1/10 - 1/100. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
WB 1/1000. Predicted molecular weight: 54 kDa.

Target

  • Function

    Regulates intra- and extracellular levels of inorganic pyrophosphate (PPi), probably functioning as PPi transporter.
  • Tissue specificity

    Found in osteoblasts from mandibular bone and from iliac bone; not detected in osteoclastic cells.
  • Involvement in disease

    Chondrocalcinosis 2
    Craniometaphyseal dysplasia, autosomal dominant
  • Sequence similarities

    Belongs to the ANKH family.
  • Cellular localization

    Membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • ANK antibody
    • ANKH antibody
    • ANKH_HUMAN antibody
    • Ankylosis progressive homolog (mouse) antibody
    • Ankylosis progressive homolog antibody
    • CCAL 2 antibody
    • CCAL2 antibody
    • CMDJ antibody
    • CPPDD antibody
    • Craniometaphyseal dysplasia Jackson type (dominant) antibody
    • FLJ27166 antibody
    • HANK antibody
    • MANK antibody
    • Progressive ankylosis protein homolog antibody
    see all

Images

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human brain cortex tissue labeling ANKH with ab211460 at 1/10 dilution.

  • Flow Cytometrical analysis of K562 cells labeling ANKH with ab211460 at 1/10 dilution (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

  • Anti-ANKH antibody - C-terminal (ab211460) at 1/1000 dilution + Mouse cerebellum tissue lysate at 35 µg

    Predicted band size: 54 kDa

References

ab211460 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab211460.
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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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